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Old May 20th, 2016, 18:14 PM   1
Bajayby
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Low fertility - Own eggs vs donor eggs decision


Hi all,

I'm a 39 year old female and have been trying (4 x IUIs) since Jan 2015 with no success so far.

I have an average AMH for my age, but this means low fertility.

I know that my next step in trying to achieve a healthy baby is to try IVF.

I have been told that the success rate of IVF using my own eggs for my age with my AMH is about 12%...but this is an estimate as everyone is different. If I use donor eggs, the success rate increases to about 65%.

Because I have low fertility, I am tasked with the decision of attempting IVF with my own eggs, or IVF with donor eggs.

No doubt that I would like to try with my own eggs.

In Ireland we don't get free attempts with our national health authority, we have to pay for fertility treatment ourselves and as you all know it's a very expensive process...but will be worth it in the end. There are a number of factors that will influence my decision; my age, my partners age, my low fertility, cost.

Has anyone been tasked with the same decision or in the same situation? Has anyone with low AMH decided to try with DE without trying with their own eggs first?



 
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Old May 20th, 2016, 19:59 PM   2
MoBaby
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I'd say if you can afford it to at least give your own eggs a shot then go for donor. We're your iuis with meds and how did you respond then?



 
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Old May 21st, 2016, 06:41 AM   3
Bajayby
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Hi MoBaby,

Thanks for your reply. Yes, my IUIs were with meds, although it was the lower dose, 75iu. I seemed to produce either 1 or two maturing (above 17mm) follicles in my cycles, with smaller ones only developing so far.

At 39 with low AMH, and not knowing if I am producing eggs, it's a difficult decision.



 
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Old May 21st, 2016, 07:22 AM   4
MoBaby
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I know. It would be. What is your resting follicle count and fsh?



 
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Old May 21st, 2016, 08:33 AM   5
Bajayby
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I'm not sure what you mean by resting follicle. I've been told that my FSH level is normal.

Did you ever get any immunology testing done? If so, is it OK for me to ask what you have done?



 
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Old May 21st, 2016, 08:56 AM   6
MoBaby
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Resting follicle or antral follicle or the baseline count. I know with ivf they always count how many baseline follicles you have. It is an indicator too of how well you'll do. Norma fsh is good as some have low Amh and high fsh which is a bad combo. Fsh being normal means you'll have a chance of responding well to meds.I only did recurrent loss panel which included a lot of blood disorders and some genetic screening. But never had nk cells tested or other immune factors. My re at the time didn't really believe in immune issues as a cause. I've had a bunch of losses without explanation so there could be some underlying issue or it could be due to the fact my uterus is abnormally shaped. But there are several here who have had it done and see reproductive immunologists so I bet you can find some info if you make a new thread.



 
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Old May 21st, 2016, 12:53 PM   7
Vonn
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This is a really difficult decision. I know because I've been there. I did 6 IUIs, changing/increasing meds each time & never got more than 2 follicles. My chances with IVF with my eggs was put at 5%. The IUIs were covered by insurance, but IVF is not, so we have to pay out of pocket. We don't have a lot of money, so as hard as it was not to give it a shot with my eggs, we may only have one chance to do this & we just have to give ourselves the best possible opportunity. That means donor egg IVF. And I am excited about the possibility that I might actually get pregnant!

One of the threads on here that I have been on had a woman who used donor eggs (after trying lots of everything), so I got to follow her journey to donor ivf identical twin girls (super interesting how that happened). It really helped me get comfortable with the idea, something I initially thought that I would never have to do, of course. (It seems like every step in this process is one of acceptance that moving on to the next level is the right move.)

There was a grieving process for me, letting go of the idea of having my own genetic child/ren. DH has been great and is really okay with it, has been ever since the first time we talked about it. He doesn't seem phased at all by the fact that his sperm will be joined with a strangers eggs. I am very thankful for that, it would have been much harder if he had struggled with the idea. And our families are supportive, as well. Certainly learning a lot about high tech fertility help, but open to whatever it takes for us to have a baby.

Everyone I have ever come across on BnB who did donor egg ivf had no regrets. But it is a tough decision and not for everyone. And most who do it have tried own egg ivf prior. We simply do not have the resources or the time to try that ourselves.

There is some interesting research out there about micro rnas and the environment (epigenetics) from birth mom really impacting the baby, affecting how the genes from the donor egg are actually expressed in a baby. This helped me to believe that I wouldn't just be carrying "someone else's baby." To me it's a no-brainer that I would want to try DE IVF rather than adoption for the experience of pregnancy, breast-feeding, etc.

I wrote quite a bit! I hope it's helpful. Good luck with your decision. Give it a little time and the right answer for you will become clear. In the meantime, feel free to stalk or join the "Inconceivable and Beyond" thread here on the Assisted Conception page. It's full of ladies on the DE IVF journey!



 
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Old May 21st, 2016, 13:24 PM   8
lisap2008
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If you can afford possible multiple cycles then I would give own egg IVF a try , I would take coq10/ubiquinol 3 months prior to starting stims and stick with high protein, low sugar diet doing this has been shown to raise the success rate.



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Old May 22nd, 2016, 05:51 AM   9
Bajayby
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Quote:
Originally Posted by MoBaby View Post
Resting follicle or antral follicle or the baseline count. I know with ivf they always count how many baseline follicles you have. It is an indicator too of how well you'll do. Norma fsh is good as some have low Amh and high fsh which is a bad combo. Fsh being normal means you'll have a chance of responding well to meds.I only did recurrent loss panel which included a lot of blood disorders and some genetic screening. But never had nk cells tested or other immune factors. My re at the time didn't really believe in immune issues as a cause. I've had a bunch of losses without explanation so there could be some underlying issue or it could be due to the fact my uterus is abnormally shaped. But there are several here who have had it done and see reproductive immunologists so I bet you can find some info if you make a new thread.
Thanks for the reply MoBaby. Hmmm, I'm not sure what my resting follicle level is. I did get a baseline US done prior to my first IUI, but I can't recall the results of that. I should have a copy of the results in my files though, I'll try find it.

I'm not sure at what point they can test for nk cells..do you know?

I'll look up some threads about immunology on here to see if I can get any more info.



 
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Old May 22nd, 2016, 06:01 AM   10
Bajayby
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Quote:
Originally Posted by Vonn View Post
This is a really difficult decision. I know because I've been there. I did 6 IUIs, changing/increasing meds each time & never got more than 2 follicles. My chances with IVF with my eggs was put at 5%. The IUIs were covered by insurance, but IVF is not, so we have to pay out of pocket. We don't have a lot of money, so as hard as it was not to give it a shot with my eggs, we may only have one chance to do this & we just have to give ourselves the best possible opportunity. That means donor egg IVF. And I am excited about the possibility that I might actually get pregnant!

One of the threads on here that I have been on had a woman who used donor eggs (after trying lots of everything), so I got to follow her journey to donor ivf identical twin girls (super interesting how that happened). It really helped me get comfortable with the idea, something I initially thought that I would never have to do, of course. (It seems like every step in this process is one of acceptance that moving on to the next level is the right move.)

There was a grieving process for me, letting go of the idea of having my own genetic child/ren. DH has been great and is really okay with it, has been ever since the first time we talked about it. He doesn't seem phased at all by the fact that his sperm will be joined with a strangers eggs. I am very thankful for that, it would have been much harder if he had struggled with the idea. And our families are supportive, as well. Certainly learning a lot about high tech fertility help, but open to whatever it takes for us to have a baby.

Everyone I have ever come across on BnB who did donor egg ivf had no regrets. But it is a tough decision and not for everyone. And most who do it have tried own egg ivf prior. We simply do not have the resources or the time to try that ourselves.

There is some interesting research out there about micro rnas and the environment (epigenetics) from birth mom really impacting the baby, affecting how the genes from the donor egg are actually expressed in a baby. This helped me to believe that I wouldn't just be carrying "someone else's baby." To me it's a no-brainer that I would want to try DE IVF rather than adoption for the experience of pregnancy, breast-feeding, etc.

I wrote quite a bit! I hope it's helpful. Good luck with your decision. Give it a little time and the right answer for you will become clear. In the meantime, feel free to stalk or join the "Inconceivable and Beyond" thread here on the Assisted Conception page. It's full of ladies on the DE IVF journey!
Hi Vonn, wow, what a post. I'm so grateful to you for sharing your story.
Do you recall the thread title that you read to follow the other lady's journey? It would be interesting to read.

I have some friends who have gone through the DE IVF journey and this was after they had tried numerous times with their own eggs. In some way the decision to move from trying IVF with your own eggs is a tiny bit easier for some than it is to not have tried with your own eggs first.

I would be interested to know how you came to accept the idea of possibly not having a biological child(ren) of your own. This is the part that I am most struggling with in regards to making my decision - trying to accept that I may not have a biological child(ren). It is like a grieving process.

I will look up the thread 'Inconceivable and beyond'.

Thanks so much again for the info, I really appreciate.



 
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