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Old Jan 7th, 2012, 12:39 PM   1
GaiaSN
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My experience with Misoprostol (Cytotec) for missed miscarriage


I went through with taking the Misoprostol for my missed miscarriage yesterday. Since I was having a hard time finding accounts on what to expect by women in a similar situation, I thought I'd post my experience with the drug here.

I got the diagnosis on Wednesday (it's now Friday) that my embryo stopped growing at around 6w5d, shortly after my first ultrasound where we heard a heartbeat and thought we were in good shape after a previous ectopic. The baby should have been at around 9w3d. My doctor gave me four 200MCG tablets of Misoprostol and told me to put two in each cheek and to allow them to dissolve there over the next 30 minutes. On the internet, I could find hardly anything about this method, - it appears that most women are told to use the drug vaginally. One site online discussed time as the biggest difference. It seems that putting them in your cheeks speeds up the process because it gets absorbed faster, but I am no doctor. The doctor also gave me a prescription for a painkiller, in my case Hydrocodone. I am just saying this ahead of time: You will need painkillers, even if you usually don't take them. Make sure to have some on hand. They then sent me home to go through this. It appears that in the US this is standard procedure. I have read that in other countries they keep you under supervision at the clinic.

Timeline:

11.20am: Took Misoprostol after talking to my dear M. I had to make sure this is the right decision one more time. Cold chills - apparently a common side effect - set in after about 20 minutes.

11.45am: Tablets mostly dissolved, with a strange dry sensation left in my throat.

11.50am: Took one tablet of Hydrocodone just to be safe and since I was already feeling a slight tinge on my left side. I read it would be better to start pain management early. I then took a hot shower to help the process along and because I at least wanted to feel and look good when going through such an undignified process, dammit. After the shower I felt the first slight cramps like menstrual cramps, and took another one of the painkillers.

12.45pm: Definitely real cramps now; getting the heating pad ready; waiting.

1-5pm: I was experiencing extremely severe cramps, and was loosing massive blood clots (they looked like chunks of liver, some of them the size of my fist.) None of the passing itself was particularly painful, just a strange sensation. I also experienced nausea and vomiting, but strangely also hunger/appetite. Every time I got up I had to go to bathroom and passed huge chunks of tissue. I went through a pad every 30 minutes, and they were immediately soaked.

3pm: Took another one of the painkillers because the pain was still very severe.

5pm: Pain all of a sudden subsided, and I was now having very mild cramps that lessened in frequency.

6pm: Got up to go the the bathroom and passed what I believe was the sack/embryo. A lump of tissue about size of my palm (about 150g), grayish in color with dark spots discernible. I almost immediately felt like this was it.

6.30pm: Had almost no pain anymore except for mild cramps, but was extremely fatigued, presumably from all the blood loss and psychological strain of the experience.

It's now the morning after, I have very light bleeding and no pain. If this was it, I will count my blessings. Going for a follow up next week to make sure it's all done.

Notes:

- I felt the effect of the drug almost immediately after taking it. This seems to be somewhat out of the norm of what I read online where women report waiting for hours, some even days and the process being much more drawn out. Reasons that I believe played a role: a) my body was ready and I would have miscarried naturally very soon anyway and/or b) delivery mechanism. Note also that it seems that for some women this drug doesn't work at all and they end up having to have a D&C.

- I vomited, but was hungry through the whole ordeal. Very strange.

- Make sure you have everything you need in place before taking the medication. Online it says you have 2-8 hours, but it set in right away for me. Make sure you have a comfortable and quiet environment.

- Regarding the pain: It was very painful, but manageable with the pain killers. On the pain scale, it came close, but didn't match the pain I experienced with my ectopic pregnancy which was treated with Methotrexate.

Ping me if you have further questions.

Update: Found another good thread online here.



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Old Jan 8th, 2012, 15:25 PM   2
Kmfc
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Glad I read this-ESP your link thank you.
I was just thinking my situation was a bit odd...

On fri I went into hosp to start my medical management. I am in uk. I was 13 weeks but baby had died at 7+6 weeks.

I had the tablets orally at 10am, 12 and 2pm. At 4pm after walking round a bit I had a small amount of spotting. And the pain started at 4.20pm, contractions about 5 mins apart. I had taken 2 paracetamol and a codeine. I left hospital and contractions got worse. At 6pm they were 1min apart and getting unbearable. At 6.20pm I felt a gush-it was my waters and when I went to the loo I passed a small heap of little clots. Nothing that I think was a nearly 8week fetus.

But then the pain stopped and I have had no bleeding since then. A tiny clot or two maybe but that's it!

Not sure til my scan in a week if I've passed it all or not-but I think not!

Anyone else had this?!



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Old Jan 9th, 2012, 15:14 PM   3
debzie
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Hello ladies so sorry for your losses and thank you for posting your accounts.

Mine will be somewhat hazy as the last one was in June last year.

I have had medical management now on two occasions the first being in november 2010 for a mmc twin pregnancy that stopped developing at around 8 weeks. On this occasional (I too am in the uk) I was given the tablets vaginally, apparently the medication is absorbed faster through mucus membranes so mouth or vaginal. I was admitted to gyne ward as a day patient.

I had a small amount of spotting and cramping but nothing much. 2 hours later I was given a further dose, I had a few cramps and then began to bleed like a heavy period.

Following the next dose I had some real contractions and began to pass clots but it stopped and I was allowed home.

I went home and that night began to have sevear pain, having been through labour I liken it to end stage labour pains, I passed clots the size of my palm too and loads of blood. This continued for two hours and then stopped, only to start again the next night. I took codeine and paracetamol for the pain but if I had stronger I would have taken it.

Second time was in June last year, this was faster, having passed everything by 7pm the same day as receiving the first dose. Again there was alot of clots and blood. At one point I was gushing blood, worried I called the nurse whom sent for the doc. I was examined and some of the placenta was caught in my cervix, the doc removed this and instantly the contractions stopped.

Again the pain was managed with codeine and paracetamol.

Hope this helps and does not terrify.



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Old Jan 11th, 2012, 10:04 AM   4
Kmfc
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Just an update from my above...
Just got back from a scan and I didn't miscarry the fetal sac so I've been given more tablets (was getting scared of ashermans syndrome with the erpc/d&c as have had 3 previously).
So I'm starting all over again
Took them at 11.30 and am starting to get period pains now (3pm).



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Old Jan 11th, 2012, 11:48 AM   5
MonkeyCymru
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Can you pace about, and possibly use a hot water bottle on your stomach/back - for me this seemed to ease the pain when I had MMC end of Sept (and the shivers that GaiaSN mentioned) but to also encourage things on their way.

I have just gone through 2nd m/c naturally, and am so sorry to hear of others who have gone through this, but also am thankful that these forums exist - they're so helpful to inform and help feel prepared.



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Old Jan 11th, 2012, 13:41 PM   6
Kmfc
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Quote:
Originally Posted by MonkeyCymru View Post
Can you pace about, and possibly use a hot water bottle on your stomach/back - for me this seemed to ease the pain when I had MMC end of Sept (and the shivers that GaiaSN mentioned) but to also encourage things on their way.

I have just gone through 2nd m/c naturally, and am so sorry to hear of others who have gone through this, but also am thankful that these forums exist - they're so helpful to inform and help feel prepared.
Yes these forums have been my rock!

Think you are right about keeping moving. I've got a hot water bottle on the go. Just hope it works this time!



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Old Jan 11th, 2012, 14:45 PM   7
GaiaSN
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Hi guys, so sorry to see you having to go through this, too

I agree that moving around and in particular the hot water bottle helped. Another good one is a hot shower (don't take a bath because of risk of infection...), because it combines both aspects - standing upright and warmth.

Good luck, I hope all goes well and you soon will be able to heal!



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Old Jan 11th, 2012, 18:20 PM   8
Kmfc
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Still nothing! Aaaah getting frustrated! Want to put the last month behind me and move on!



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Old Jan 16th, 2012, 19:13 PM   9
Jezzielin
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My doc gave me 6 pills to take, 2 per day for three days... Is this the norm?



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Old Jan 16th, 2012, 19:22 PM   10
Kaylattc
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Thank you for posting! I am about to go through this, this week.

In the past I did it naturally but to speed up getting me pregnant again he wants to give me medication.

Do y'all feel like you would rather o done naturally or did the pill help pass easier?
I am very scared and nervous. I know I am under 7 weeks but I don't know exactly how far along I am going for ultrasound in a couple days......

I wonder if he will do ultrasound first he didn't say. He just said he was going to call meds into my pharmacy.



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cytotec , experience , miscarriage , misoprostol , missed

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