Low AMH and recurrent miscarriage? - Page 2

bumpyplease · Oct 31st, 2011, 07:29 AM

Quote:

Originally Posted by Candy Cane

Quote:

Originally Posted by bumpyplease

Hi Ladies,

First of all i apologise for coming into your area when technically i dont qualify! (im 30), but someone suggested i post in here as some of you wonderful ladies may be able to help.

just to give you a bit of background i have no children and have been TTC for a year and have had 3 MC.

I have just completed my recurrent miscarriage testing and went in for my results yesterday. All of my test results were fine except for one. And that is my ovarian reserve. I have low AMH levels (anti mallerian hormone) which means my egg quality is poor. My consultant said he was shocked at the levels for my age as usually the levels become lower when you get a bit older. He also said usually people would find it difficult to conceive, but obviously not in my case!!

It was one of the worst outcomes for me as there is nothing they can do to improve things. his advice was to just continue to try hoping that one will be lucky! i dont even fit in the criteria for IVF as he said since i am falling the wait will be 3 years for me!

im obviously devastated as time is of an essense now so we just need to keep trying and hope that we may get lucky. I hate not being able to do anything/take anything to improve the odds though.

Has anyone else been told they have low AMH levels or know anything about it?

Also most of my research leads to people with low AMH levels that struggle to concieve, i seem to be able to conceive but miscarry every time at around 8 weeks. anyone else going through something similar?

thanks for reading and

to you all!

I'm so sorry for your troubles and hope you are finding the answers you are seeking. I can't answer your post specifically since I am not as far down the road as you are, but maybe I can be cheeky and ask for your help? I am 37 and have had three miscarriages this year just like you. Each one is lost between the 6-8 week mark, one was silent and the others were normal.

I have now been referred to a reproductive medicine unit at Whipps Cross Hospital in London for testing and wondered if you would be able to tell me what I can expect please? I know each health service is different in some ways but generally speaking, what did you have to go through and how long did it take for you to get your results? Did your partner have to have any tests?

As I said I am sorry I can't answer your question and hope you don't think me selfish asking you the question instead!

Sorry candy cane - i just realised i didnt respond to your questions. you are not cheeky at all! that is what this forum is for, for us to all be able to hopefully help and support each other!

I actually had private testing under my works medical insurance so it was incredibly quick for me. The NHS wait for me would have been 12 weeks for the first appointment but I managed to have a first consulatation, ultrasound scan, full blood testing and results back in 4 weeks! They will usually offer you an ulstrasound (internal) to check for fibroids, PCOS, and make sure everything looks ok, then the blood tests are for many different things, thrombophilia (blood clotting), progesterone, thyroid etc. I had the karyotyping and my OH did as well. He didnt have the sperm analysis though as he already has one child so thought it would be clear. The AMH test i had is not frequently done on the NHS yet, apparently, some are still relying on the day 3 FSH test but apparently this is a new test and much more reliable so its becoming more popular. Strangely enough my FSH test was normal and usually they would expect some correllation between the two.

Next time im pregnant i will be offered early scans and also be put on cyclogest (progesterone) to see if that helps although I have not been diagnosed with a specific progesterone problem.

Good luck with your testing, sorry for rambling

filipenko32 · Nov 6th, 2011, 07:04 AM

Hi Bumpy

I just came across this thread whilst browsing, I wondered what your number acutually was for the AMH as mine was 17 point something and lesley regan at the recurrent mc clinic said it was nothing to worry about even though it fell in the 'low fertility' bracket she shrugged it off.

Also bumpy the consultants who saw this result really looked down on it as it was taken only 10 days after my 2nd miscarriage and there is some evidence to suggest that even AMH is not reliable of normal ovarian reserve so soon after pregnancy. Was yours taken soon after pregnancy?

Also my antral follicle count is 20 which is normal for my age 32. Did you have your estrogen measured with your fsh?

If you get pregnant quickly this is not a sign of diminished ov reserve as I have heard from many of the docs ive seen.

bumpyplease · Nov 7th, 2011, 04:25 AM

Quote:

Originally Posted by filipenko32

Hi Bumpy

I just came across this thread whilst browsing, I wondered what your number acutually was for the AMH as mine was 17 point something and lesley regan at the recurrent mc clinic said it was nothing to worry about even though it fell in the 'low fertility' bracket she shrugged it off.

Also bumpy the consultants who saw this result really looked down on it as it was taken only 10 days after my 2nd miscarriage and there is some evidence to suggest that even AMH is not reliable of normal ovarian reserve so soon after pregnancy. Was yours taken soon after pregnancy?

Also my antral follicle count is 20 which is normal for my age 32. Did you have your estrogen measured with your fsh?

If you get pregnant quickly this is not a sign of diminished ov reserve as I have heard from many of the docs ive seen.

Hi

how are you? thanks for responding to my thread. My result is quite a bit lower, only 4.7. apparently 2.2-15 is low and above that is normal or something. below 2.2 is very low/unfertile so I have come out fairly near the bottom of the low category

So 17 for you wouldnt be particularly low if the figures i have been quoted are accurate. Mine was taken about a month after miscarriage.

Apparently though there should be a correlation between AMH and FSH yet my FSH reading was entirely normal. My consultant was also baffled that i am getting preg so quickly as he thinks i should be struggling right now, but i have a letter from him that says the low number does indicate diminshed ovarian reserve and may well explain my recurrent miscarriages. He does however point out that there is every chance I will conceive again and go on to have a full term delivery so fingers crossed!

thankks for the PM message by the way! I see you are 4dpo, i am 7dpo so we will be testing about the same time!

When are you testing? Im going to test i think on thursday at 10dpo xx

filipenko32 · Nov 7th, 2011, 04:43 AM

Hi Bumpy, oh i'm sorry, do you know what may have caused it? I have read lots and lots of posts where women have conceived and had no trouble carrying to term with scores lower than yours. And the fact you're getting pregnant so quickly and your fsh is good is a great sign.

I hope we both get our bfps soon x x x

SRD35 · Jan 2nd, 2013, 07:49 AM

Hi All,

I totally feel your pain bumpyplease. I have had 3 miscarriages and after investigation have an AMH of under 2 which is in the very low - infertile catagory. At 35 this was a bit of a shock as I am sure you can relate to. I was told that AMH is about egg reserve rather than quality and this is more determined by the age of the eggs, which is your age. However they did say that theroetically speaking if you have a limited number left you are "scraping the bottom of the barrel". I know not the best expression but does kinda make sense. I did see an IVF specialist and she advised this would increase my chances of carrying fullterm. She also offered this new technique where they video the eggs dividing to see which one's divide at a steady rate. Normally they put them in a dish and leave them for 3 days. This means that some could develop with growth spurts and so not be as goos and the steady eddies. If you do go down this route maybe this would be worth looking into. Lastly some hope....I found out on christmas day that I am expecting again. Am reserving the excitment for week 12 but whichever route you take you always have to start with the white stick showing two lines so yay for that. Really good luck to you I am sure you will get your dream xx

bumpyplease · Jan 2nd, 2013, 09:51 AM

Hi srd35, this is an old thread from over a year ago and I'm happy to report I now have a gorgeous 4 month old boy after suffering from 4 mc in a row!!! Fili (also on this thread) is about to give birth after also having 4 mc in a row. I never thought they would but our dreams came true!!! Looks like I found a good egg after all! For any other ladies out there still trying I took coq10, and also pregnacare.

Congrats on your bpf xxx

Nov 6th, 2011, 07:04 AM	#12
filipenko32 Other BnB Elite Join Date: Aug 2011 Location: London UK Posts: 10,200	Hi Bumpy I just came across this thread whilst browsing, I wondered what your number acutually was for the AMH as mine was 17 point something and lesley regan at the recurrent mc clinic said it was nothing to worry about even though it fell in the 'low fertility' bracket she shrugged it off. Also bumpy the consultants who saw this result really looked down on it as it was taken only 10 days after my 2nd miscarriage and there is some evidence to suggest that even AMH is not reliable of normal ovarian reserve so soon after pregnancy. Was yours taken soon after pregnancy? Also my antral follicle count is 20 which is normal for my age 32. Did you have your estrogen measured with your fsh? If you get pregnant quickly this is not a sign of diminished ov reserve as I have heard from many of the docs ive seen.

Status: Offline

Nov 7th, 2011, 04:43 AM	#14
filipenko32 Other BnB Elite Join Date: Aug 2011 Location: London UK Posts: 10,200	Hi Bumpy, oh i'm sorry, do you know what may have caused it? I have read lots and lots of posts where women have conceived and had no trouble carrying to term with scores lower than yours. And the fact you're getting pregnant so quickly and your fsh is good is a great sign. I hope we both get our bfps soon x x x

Status: Offline

Jan 2nd, 2013, 07:49 AM	#15
SRD35 Pregnant (Expecting) New BnB member Join Date: Dec 2012 Posts: 3	Hi All, I totally feel your pain bumpyplease. I have had 3 miscarriages and after investigation have an AMH of under 2 which is in the very low - infertile catagory. At 35 this was a bit of a shock as I am sure you can relate to. I was told that AMH is about egg reserve rather than quality and this is more determined by the age of the eggs, which is your age. However they did say that theroetically speaking if you have a limited number left you are "scraping the bottom of the barrel". I know not the best expression but does kinda make sense. I did see an IVF specialist and she advised this would increase my chances of carrying fullterm. She also offered this new technique where they video the eggs dividing to see which one's divide at a steady rate. Normally they put them in a dish and leave them for 3 days. This means that some could develop with growth spurts and so not be as goos and the steady eddies. If you do go down this route maybe this would be worth looking into. Lastly some hope....I found out on christmas day that I am expecting again. Am reserving the excitment for week 12 but whichever route you take you always have to start with the white stick showing two lines so yay for that. Really good luck to you I am sure you will get your dream xx

Status: Offline

Jan 2nd, 2013, 09:51 AM	#16
bumpyplease Mum (Mom) Chat Happy BnB Member Join Date: May 2011 Posts: 2,042	Hi srd35, this is an old thread from over a year ago and I'm happy to report I now have a gorgeous 4 month old boy after suffering from 4 mc in a row!!! Fili (also on this thread) is about to give birth after also having 4 mc in a row. I never thought they would but our dreams came true!!! Looks like I found a good egg after all! For any other ladies out there still trying I took coq10, and also pregnacare. Congrats on your bpf xxx

Status: Offline

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