Symptoms before implantation

ellieb31 · Jun 9th, 2010, 08:42 AM

This subject comes up quite a lot and I thought I'd share what I found (thank you google) on the subject. For those of you that think you're going crazy because you're having symptoms before implantation and you don't think that you should be...you're not crazy!!

There are very few, if any, pregnancy symptoms before implantation, since the embryo has not begun to make hcg. However, your body does not continue *as normal*, or with business as usual. After hatching from the zona pellucida, the embryo sends a signal to the ovaries to secrete early pregnancy factor (EPF), which occurs from 1-2 days after fertilization. This EPF begins a dialogue between the embryo and the mother. It is possible, therefore, that a woman who is very sensitive, or is accutely aware of things, may have some symptoms associated with the EPF secretion, although I am not sure if this has been studied.

EPF is an immunosuppressant. Along with other substances associated with early embryos, EPF believed to play a role in preventing the immune system of the pregnant female from attacking the embryo. In humans, modern pregnancy tests detect human chorionic gonadotropin (hCG). hCG is not present until after implantation, which occurs six to twelve days after fertilization. In contrast, EPF is present within hours of fertilization. While several other pre-implantation signals have been identified, EPF is believed to be the earliest possible marker of pregnancy. The accuracy of EPF as a pregnancy test in humans has been found to be high by several studies.

Dinah · Jun 9th, 2010, 08:47 AM

Oh now this is interesting because it lowers your immune system if I'm reading that right and I currently am 11DPO and have a chest infection which started Friday (6DPO). Now obviously I could get ill at any time but I do find that link interesting so thanks for posting!

- Dinah

inkdchick · Jun 15th, 2010, 07:23 AM

wow thats fantastic - i have had whats felt like a cold starting about 5 days ago and there is nothing so that could have been that how cool

Bettydraper · Mar 21st, 2012, 14:45 PM

Bumping this thread as I've never thought of this, sounds very interesting to me as I symptom spot at 5 dpo

iiTTCii · Nov 20th, 2012, 03:06 AM

Bump

Zeri · Nov 20th, 2012, 07:58 AM

Very interesting!

Misscalais · Apr 21st, 2013, 21:28 PM

Bump

clairebear0 · Apr 21st, 2013, 23:22 PM

Quote:

Originally Posted by Bettydraper

Bumping this thread as I've never thought of this, sounds very interesting to me as I symptom spot at 5 dpo

What does it to mean to "bump"?

bubbles1013 · Apr 22nd, 2013, 00:15 AM

Quote:

Originally Posted by clairebear0

Quote:

Originally Posted by Bettydraper

Bumping this thread as I've never thought of this, sounds very interesting to me as I symptom spot at 5 dpo

What does it to mean to "bump"?

Sends the whole topic to the top of the list... pretty sure.

Jun 9th, 2010, 08:42 AM	#1
ellieb31 Pregnant (Expecting) Chat Happy BnB Member Join Date: May 2010 Location: Southampton, UK Posts: 2,030	Symptoms before implantation This subject comes up quite a lot and I thought I'd share what I found (thank you google) on the subject. For those of you that think you're going crazy because you're having symptoms before implantation and you don't think that you should be...you're not crazy!! There are very few, if any, pregnancy symptoms before implantation, since the embryo has not begun to make hcg. However, your body does not continue as normal, or with business as usual. After hatching from the zona pellucida, the embryo sends a signal to the ovaries to secrete early pregnancy factor (EPF), which occurs from 1-2 days after fertilization. This EPF begins a dialogue between the embryo and the mother. It is possible, therefore, that a woman who is very sensitive, or is accutely aware of things, may have some symptoms associated with the EPF secretion, although I am not sure if this has been studied. EPF is an immunosuppressant. Along with other substances associated with early embryos, EPF believed to play a role in preventing the immune system of the pregnant female from attacking the embryo. In humans, modern pregnancy tests detect human chorionic gonadotropin (hCG). hCG is not present until after implantation, which occurs six to twelve days after fertilization. In contrast, EPF is present within hours of fertilization. While several other pre-implantation signals have been identified, EPF is believed to be the earliest possible marker of pregnancy. The accuracy of EPF as a pregnancy test in humans has been found to be high by several studies.

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Jun 9th, 2010, 08:47 AM	#2
Dinah Mum (Mom) BnB Addict Join Date: Oct 2009 Posts: 3,321	Oh now this is interesting because it lowers your immune system if I'm reading that right and I currently am 11DPO and have a chest infection which started Friday (6DPO). Now obviously I could get ill at any time but I do find that link interesting so thanks for posting! - Dinah

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Jun 15th, 2010, 07:23 AM	#3
inkdchick Other BnB Addict Join Date: Jul 2009 Posts: 3,982	wow thats fantastic - i have had whats felt like a cold starting about 5 days ago and there is nothing so that could have been that how cool

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Mar 21st, 2012, 14:45 PM	#4
Bettydraper Other Active BnB Member Join Date: Oct 2011 Posts: 232	Bumping this thread as I've never thought of this, sounds very interesting to me as I symptom spot at 5 dpo

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Nov 20th, 2012, 03:06 AM	#5
iiTTCii Pregnant (Expecting) Active BnB Member Join Date: May 2012 Location: England Posts: 938	Bump

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Nov 20th, 2012, 07:58 AM	#6
Zeri Mum (Mom) Chat Happy BnB Member Join Date: Apr 2009 Location: Caribbean Posts: 1,738	Very interesting!

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Apr 21st, 2013, 21:28 PM	#7
Misscalais Pregnant (Expecting) Chat Happy BnB Member Join Date: Sep 2012 Location: Australia Posts: 1,918	Bump

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