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Old Sep 18th, 2008, 09:56 AM   1
chocci
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FSH, LH and Progestrone - 21 days blood Tests


Hi

I hope someone can help explain things as I am totally confused

My husband and I have been trying for a baby for over a year now. My periods were always regular i.e. between 25-28 days. I came off the pill last year and have been regular since then. I was slightly concerned I do not bleed much only for 1-2 days max, but was told not to worry about that.

Everything was fine and I knew it can take 2 years to conceive for some couples but as time goes on I am starting to get a little more concerned.

Last few months my periods suddenly came at 23 days, 21 days then 17 days, I decided I best go to see doctors. They asked me to come in for 21 day blood tests to check various things. I have just got the results but am slightly confused and am hoping someone has had the same and can explain.
Thyroid tested OK
Cholesterol great very low at 3.1
FSH 2.1
LH 1.6

The nurse had a nightmare getting my blood and unfortunately did not managed to get enough for progesterone test on day 21, I had it taken on day 25 when they again also checked diabetes, iron blood count everything. All apparently came back "normal". I felt relieved then thought well why on day 25 is my progesterone measured as normal. I thought this had to be taken at a certain time of the cycle? On day 25 when it was taken I started my period, so how has my progesterone level been calculated?

I also don't understand what the significance of LH and FSH is at day 21? I thought this should be taken in early cycle such as day 3? Can anyone tell me what the FSH and LH level should be on day 21? and if they are at all relevant?

The nurse has said all my results are normal, which I am utterly greatful for but am bemused as to how they can all be normal when they were taken at strange times in my cycle? I am so puzzled

Oh and just to add my cycle went back to 25 days this month??? I had started using Valerian a herbal calming table and drinking chamomile tea too and think that my "wonky" periods may have been due to this? I stopped them all this month and low and behold periods returned to normal. Anyone any experience of this too?

Thanks in advance for any advice



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Old Sep 18th, 2008, 10:53 AM   2
happy mum
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it all sounds very confusing, sorry i can't help. i've got my 21day bloods on tue next week, think i'll be taking a pen and paper for some info. if you don't find out before i'll ask.maybe you should make an appointment with dr to explain things better??? good luck!! i have a similar prob !!!



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Old Sep 18th, 2008, 11:53 AM   3
chocci
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If I find out I will let you know. I have asked for the nurse / doctor to ring me for an explanation, told hubby might be time for him to go get checked because apparently thus far tests have found nothing wrong with me

Will keep you posted would be good if you could let me know how you get on and if you find out anything interesting to shed any light on the topic?



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Old Sep 18th, 2008, 14:13 PM   4
meisha
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hello there, i have just had these tests done BUT LH and FSH were done on day 3 as they should always be done. I really cant tell you what these levels should be on day 21 as I dont know what the reason for having them taken on this day would be.
Boook in and go see your doc.
Progesterone can be take late. Min should have been on 26 but I had it on 27 because of the weekend. My last test result was 84 which shows a huge increase following ovulation so if you manage to get your bloods done look for large surges.



 
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Old Sep 21st, 2008, 04:58 AM   5
chocci
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Apparently one of the first test they do if you are at all concerned about fertility, is to do day 21 blood tests. The theory is based on the most common cycle being 28 days. Therefore day 21 would be 7 days after you had ovulated on day 14. this is apparently the best time to check progesterone. They also say that FSH and LH can be taken at this time as they can compare levels of the FSH and LH to the progesterone level, apparently that relationship is the most important part of the tests and FHS and LH and progesterone levels in isolation dont mean that much it is the correlation between the 2. Apparently if there is a mismatch in the readings they would investigate further and then order FSH and LH level test on day 3. That is what i have found out so far anyway! It appears all docs are different tho and people get told all sorts of different things. I have been told the correlation between my results is good. That doesn't help me tho. I have really light periods which surely is not normal. Its like i don't build up enough womb lining which leads me to think i have a lutal phase defect and don't have high enough progesterone levels at end of cycle. No one seems to be able to offer any answers which is frustrating. I have booked to talk to nurse to see what the next steps are an I will be asking lots of questions now as i don't want to be fobbed off!!

Has anyone else had experience of these 21 day test, can you shed any light on them. And meisha, does the large surge mean good or bad? ids that good news for you or not?

I will come back after seeing the nurse and give update too as surely someone else may find this useful.



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Old Sep 21st, 2008, 09:13 AM   6
loopylew
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Quote:
Originally Posted by chocci View Post
Apparently one of the first test they do if you are at all concerned about fertility, is to do day 21 blood tests. The theory is based on the most common cycle being 28 days. Therefore day 21 would be 7 days after you had ovulated on day 14. this is apparently the best time to check progesterone. They also say that FSH and LH can be taken at this time as they can compare levels of the FSH and LH to the progesterone level, apparently that relationship is the most important part of the tests and FHS and LH and progesterone levels in isolation dont mean that much it is the correlation between the 2. Apparently if there is a mismatch in the readings they would investigate further and then order FSH and LH level test on day 3. That is what i have found out so far anyway! It appears all docs are different tho and people get told all sorts of different things. I have been told the correlation between my results is good. That doesn't help me tho. I have really light periods which surely is not normal. Its like i don't build up enough womb lining which leads me to think i have a lutal phase defect and don't have high enough progesterone levels at end of cycle. No one seems to be able to offer any answers which is frustrating. I have booked to talk to nurse to see what the next steps are an I will be asking lots of questions now as i don't want to be fobbed off!!

Has anyone else had experience of these 21 day test, can you shed any light on them. And meisha, does the large surge mean good or bad? ids that good news for you or not?

I will come back after seeing the nurse and give update too as surely someone else may find this useful.

I have a short luteal phase and have never had cd 21 tests done, my GP looked at my chart and referred us stright away to a fertility consultant, im going back next Tues to insist on a cd21 test, to think that if she'dve done the tests i might just need progesterone tablets and saved months of heartache. How do you know you have a LPD? are you charting?



 
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Old Sep 21st, 2008, 14:16 PM   7
magicvw
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Hiya! I had cd 3 and cd 21 tests - I had the cd3 first, because I went to arrange the tests on cd1 so there was time. CD3 they did lh and fsh and full bloods including glucose, and cd21 was only progesterone. There is a good link with the "normal" levels on :

http://www.fertilityplus.org/faq/hormonelevels.html

(thanks krissi!)



 
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Old Oct 18th, 2008, 08:33 AM   8
Trying4ever
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Hey Chocci,

Did you find out what your levels meant? You said you would get back after seeing the nurse last month. I also had a blood test done on day 2 and then the GP asked to have one on day 21 before she could refer me (which I did on 29th Sept 2008). My results on day 21 were:

FSH=5.1iu/L
LH=14.2iu/L
Progesterone=3.5nmol/L

My doctor just said the results are normal then referred me. I can't get hold of my day 2 tests. I'm still waiting for my referral letter. But I know there is something wrong with me cos my periods have been longer than 35 days since I have been monitoring them in Jan 2008. Once it was nearly 80 days before I had a period.

I've tried to look up the results on the net but I get confused with the units as they are mg then nmol sometimes.

Can anyone help me interpret them?



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Old Oct 18th, 2008, 10:12 AM   9
DebsHopeful
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Hi Chocci,

Take a look at this website it is super handy for interpretting your results.

fertilityplus.org/faq/hormonelevels.html

I had my 21 day blood test last Sunday and have done all the research, but unfortunately from everything I have read so far, I think your progesterone is too low and you probably aren't ovulating at the moment.
This isn't a big problem, if you go see your gynea he will help you to regulate your hormone levels and you will have your baby.

All the sites vary but the majority of them say your Progesterone has to be above 10 for ovulation but there are a couple that say you can ovulate if it is above 6.5.

Best of luck



 
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Old Oct 18th, 2008, 11:48 AM   10
Loo
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Well this is what my research has told me:

Chocci - Ideally FSH and LH should be taken early in the cycle. This is because both of them should be quite low at that time and so are easy to interpret.

If one or both of them are high then it is worrying. However, the levels of them rise naturally at midcycle time and so this could be confused with abnormal if they were taken at midcycle.

However, if they are taken later in the cycle and are low, then its ok to say they are normal, as it must have been after they had settled back down after their midcycle peak.

Yours was almost on CD1 as you started your AF that day, so really they were only a day or two early.

Trying4ever, I agree with Debshopeful about the progesterone. But did you have a period a week after your bloods? If not, then it may be that the test was not at the right time anyway. If your periods are 35 days, you should have had the progesterone on CD 28. So they may have missed your peak.

Sometimes the other thing is that if your LH is higher than your FSH (this is based on day 2 bloods though) then it may be a sign of pcos. And that would fit with your long cycles too.

Anyway, good luck to you all when you see the specialists x



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