I do, and so does OH, and it's very very hard! And we also have no family near us.
Essentially, my OH is the main earner now, because my LO is like yours, she won't sit still for more than 5min in any given situation, before she starts getting very unhappy.
She requires tremendous efforts most days, to put her to sleep during the day, which doesn't help either.
I think what we have come to realise, is that something has to give: Either you let the house chores go to the wayside, or your work becomes a luxury.
I was getting very stressed out, as my work was just constantly interrupted, then by the time I finally had her alseep, it was time for cooking, cleaning, running an errand or I was just too tired to focus!
Now, we've decided that I wouldn't put so much pressure on myself and if I get to do some work, great (I'm a consultant, so I get to take as many/little jobs as I like), but if becomes too much, I scale back.
I would definitely 2nd the pp: Naptime is the ONLY time I get to do any work. If I'm lucky, I get to do house stuff while she is up, and move her around the house as I'm moving. That frees up the naptimes for work, rather than domestic stuff. But there are days when that's just not possible.
Our expectations have changed dramatically since our LO arrived, I think we were really naive before, and thought she would somehow fit into our lives...
We often wondered how on earth did other couples manage, and the answer is simple:
They either have a nanny, drop their kids off at the nursery, have family to babysit, or are a single-income household. No magic trick ;-)