I voted yes, as I do use it every change regardless, only cause we were advised by hospital staff and Drs. Chloe had a bad nappy rash that casued the skin to break down and for 8 weeks it was hell. We were prescribed a spray called Cavilon and it was a godsend. I brought more from ebay cheap, and now if she looks a little red I use the spray for the day, otherwise its the cream. I probably use waaaaayyyy too much, I think were going through a 250g tub every 3 weeks! But Id rather be safe than have Chloe go through that again.