None have fertilized

[Greta]

Hi, I know I should probably set up a journal instead of write these miserable posts! but I just didn't use it much last time.

Anyway, I posted last week to say my IVF cycle was looking uncertain as the eggs were developing slowly. Well I was put on Menopur for two days longer and by Friday I had responded well and there was at least 10 follicles doing well. I went for EC on Sunday and they got six eggs.

I kept thinking, wouldn't it be terrible if none fertilized as I waited for that scary call.

Anyway, the call came and that is what has happened! They don't know why. They said the sperm looked good and was still swimming around and five of the eggs looked OK. But it has just not fertilized them. I asked if it was my age (40) and they said they don't think so as this happens occasionally across all ages. My husband has 50% antibodies and they previoulsy said this would not affect treatment and I guess these have been removed before they put them together? I am starting to wonder now though.

They said most problems could be overcome with ICSI, so hopefully we will try that now. But my hope is really fading and I feel so gutted.

Has anyone had this before or know why this could happen? Thanks, Greta. xx

 

[Oneday]

I'm so sorry but you can't give up hope 10 eggs was a great number and hopefully another go with isci will give you some good embies and a bfp. Take care of yourself

 

[tansey]

So sorry to read that none fertilised

 

[BigFoot1980]

I am so sorry hun. But ICSI can overcome that problem. So don't loose hope.

 

[Greta]

Thanks. Just trying to understand what happened and wondering if my old eggs are to blame? x

 

[mwmm]

Hi Greta,
So sorry to hear about the zero fertilization,it is devestating when this happens.
I had exactly the same explanation,they just didn't know why-I had 27 eggs with my first ivf and only 1 fertilized,they just wasn't able to identify the problem at all-More recently,i have just had icsi, and on this cycle i had a 25% fertilization rate(10 out of 33 egss),we managed to have 1 blast transferredso are waiting to see if it worked.
The embryologist still cannot find any abnormalities too explain our low fertilization,i am only 32,my partner is in his 40's,and the only thing that they have ever noted was a weak positive for antibodies when they did the SA.
There is hope with icsi for low fertilization,*big hugs*.

 

[Beckic]

Hun I am so sorry to hear this - esp. after all the ups and downs you went through with your cycle.

I have a similar situation with the eggs on my right ovary - although the FS says he cant see anything wrong with them they never fertilise. We had straight IVF our first two cycles and both times the eggs from my right ovary diid not fertilise. They said that both the eggs and the sperm looked fine but they just showed no signs of fertilisation.

The last time around we went for ICSI and got three eggs from my right - two were immatrue and even with ICSI didnt fertilise - btu one did and went on to make a grade 1 embie.
(and as we talked about before - I think they did my EC v early cos of that one large follie - so I think the other two were just too immature to fertilise even with ICSI).

So - def. dont gve up hope sweets cos ICSI can make eggs that wouldn't fertilise on their own fertilise - I promise - just like it did with my one good egg.

And 10 is FAB hun - its really good news and going into your next cycle when you are strong enough you will be armed with all this info and they will be able to adjust your stimms dosage accordingly and do ICSI - and there is no reason why you wont go on to get that BFP.

I know its such an awful time for you right now - be good to yourslef and know that once these next few awful days are over your hope and strength will come back and that the next cycle coudl be the one for you.

Bx x

 

[Greta]

Thanks, that's really sweet and gives me hope. It's weird how only one of your ovaries is doing that. I wonder why that could be?

I spoke to the embryologist today and she said one egg was dark but three looked good. But only one or two spm were trying to pentrate each egg when they normally see "a flower" of them. So I don't know what that shows. But she sounded hopeful that we may try ICSI. At least we may be getting to the root of what is wrong - a fertilization issue. I mean I ovulate properly and we have been ttc every month for about 20, so there is something going wrong. I am still down but going to have a couple of months to recover and build my marriage cos as you are all know it is strain in many ways. Especially cos you both feel guilty about it. But I also feel my DH and I are closer because of our problems in a way. xx