Hello all, as I try to work my way through the 2300 pages of this thread, I thought I'd say hello and post some of my info, in the hope of getting some insights that could help with my situation.
But first, I am so sorry to read about all the loss here. My husband and I understand much of the pain.
I am late-30's, as is my husband. Back in our early 20's we experienced 6 mc's, over the course of a few years, all discovered at almost exactly 10 weeks, after which we gave up trying for a long time.
Back at that time, our mc's were chalked up to my immunological response to the placenta. Category II antibodies to phospholipids & Category V elevated CD 56+ natural killer cells and elevated CD 19+5+ cells. I was treated with heprin, aspirin and an immune suppressant drug, humira.
None of this worked and I had a tubal ligation.
Fast forward to last year. We had a friend kindly offer to GC for us. My husband and I both underwent all the health pre-testing required by California. We both had FDA STD testing. I had some immune assays done - TH1:TH2 cytokine ratio. Also Consyl Family Prep screen. We were told that we checked out - that we were good to go - that we'd have the normal chances of other couples, that my auto-immune issues would no longer be in play.
Our GC has had two successful, easy births. The last was around a decade ago. She is now 35. Unfortunately, she ran in to the same problem we did all those times - miscarried at 8 weeks or so. We think if she weren't getting such frequent US, that she might have found out around 10 weeks, like we did. So, this causes us to fear that our problem way back when might not have just been my immunity, but rather, maybe something about our genetics causes mc around 8 - 10 weeks.
We are willing to get whatever testing done that we need to. Just looking for guidance as to what to ask for.
We just lost 2 embryos (the clinic tried a double implant, because of our age they said). We have 5 more. 4 mid-grade, 1 lower grade blastocysts.
I should point out our GC experienced a uterine aneurysm (small subchorionic hemorrhage) at around 6 weeks. We were told that is was likely non-problematic. Our two little ones had healthy hearbeats right around 8 weeks, then by the time of our next test at 9 weeks their heartbeats were gone. This was just around 4 or 5 days ago. We are quite heart-broken.
Our GC also had a 4.5 cm cyst on one ovary, but we were told that was not a factor. Her blood tests checked out, but maybe we should have treated the cyst before implanting? Maybe we should have monitored hormone levels more closely?
If we need to, we may look in to donor egg or donor sperm. Our GC is willing to get whatever testing we'd like. She will probably D/C soon. She is also willing to help us try again.
Any advice is greatly appreciated. Sorry if any of this is unclear. I am more than happy to clarify anything.
Thank you,
QoC