Ordinarily I eschew gender stereotypes, but in this case my experience leads me to say HELL YES, boys are exhausting.
I have two boys, aged 4 and 18 months, and they are both very high energy, very physical, never sit still, jumping off the walls types. They are legit crazy.

I am permanently exhausted keeping up with them. And I say this in the sense that they are completely developmentally normal in every way, they are just little balls of energy who run everybody ragged.
My brother has two girls of similar ages and my parents babysit each set of kids regularly and they say without a shadow of a doubt that the two girls are much less exhausting to look after.
Also, for those interested, there has been actual scientific research conducted that shows that having boys may shorten a mothers life. No joke, you may lose 34 weeks of your life for every boy you birth to.

There is an article here published in the journal Nature from 2013 talking about it.