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In laymans terms: if a woman is short on folate [folic acid], B6 and B12, or has a genetic errorr, known as MTHFR or CBS, and cannot properly absorb these vitamins, the woman will develop high level of homocysteine, the sulphur that should not be present in our bodies in high amounts, which is normally suppressed by normal levels of B6, B12 and folic acid. When that happens, a woman can become infertile, or will have problems with implanting an inseminated egg, or have tubal/placenta issues, or miscarry, on most occasions more than once.