I just used PreSeed for the first time last night. I'm expecting O in the next couple days. This is cycle 9 of ttc #1, thought I'd try something different this cycle. I'll keep you updated if I get a BFP, I could be relatively certain that it was the PreSeed that helped!
The one problem I noticed was, I usually watch my CM, couldn't tell today if it was residual lubricant or CM I was feeling.