Anyone had cvs testing?

[twinkletots]

I have been offered the option of having either CVS or amniocentesis.
I am currently swaying towards the CVS option as it can be done earlier in the pregnancy but am petrified of the risks.
Just wondering if anyone has been through this test?

 

[joeyjo]

I don't know why you are being offered these so the following may not be relevant

I am high risk for T21 (downs) we declined CVS and amnio, the risks are low but were too high for me as I plan to continue regardless of results. I am paying (£500) to have a genetic blood test for T21, T18, T13 and sex chromosome abnorms. It will help us plan if necessary.

Good luck whatever you decide

 

[twinkletots]

I don't know why you are being offered these so the following may not be relevant

I am high risk for T21 (downs) we declined CVS and amnio, the risks are low but were too high for me as I plan to continue regardless of results. I am paying (£500) to have a genetic blood test for T21, T18, T13 and sex chromosome abnorms. It will help us plan if necessary.

Good luck whatever you decide

I already have a daughter with Down's syndrome which is why I have been offered them. Love my baby girl to bits but she gave us a shock when she was born as we got a low risk rating from antenatal screening in my last pregnancy so really need to know this time.
When are you getting the blood test?

 

[joeyjo]

it must be a tough emotional time

I'm having the blood test on 23rd dec - I'll be 15weeks, you can have it any time from 10weeks. The results take about 2 weeks.
It still gives a risk factor rather than a definitive yes or no but is a lot more accurate than standard screening. I'm having it done in the UK (I live in Spain) as it is more widely available & a tiny but cheaper! They do recommend a CVS or amino if you get a high risk result and are not planning on continuing but I think they quote over 99% of high risk results are positive.

 

[twinkletots]

I did think about the blood test but because we slipped through the net last time, I feel the need for a 100% definite yes or no !
Wishing you all the best for your blood tests and please let me know how you get on.
Either way, you're going to get a beautiful little bubba. Congratulations!

 

[joeyjo]

I did think about the blood test but because we slipped through the net last time, I feel the need for a 100% definite yes or no !
Wishing you all the best for your blood tests and please let me know how you get on.
Either way, you're going to get a beautiful little bubba. Congratulations!

Thank you

Good luck to you too. X

 

[HBGirl]

I had a cvs. It was not bad at all. Hurt like a bitch for a second then it was over. I felt tender and bruised for 48 hours but had no cramping or spotting at all. Quick, easy and totally worth it in the long run.

 

[Krissykat1006]

I won't be doing either, with my first child I had a CVS and nothing came back high risk, all scans were normal and when he was born we were surprised to find out he had Down Syndrome! So for me personally I feel what's meant to be will be so I'm just going with that

 

[twinkletots]

I won't be doing either, with my first child I had a CVS and nothing came back high risk, all scans were normal and when he was born we were surprised to find out he had Down Syndrome! So for me personally I feel what's meant to be will be so I'm just going with that

I thought CVS was a diagnostic test? So it tells you for definite if certain chromosomal anomalies are present or not. Are you sure you had a CVS test last time as they don't normally offer it unless you are high risk?
I know the screening tests are not diagnostic as I too came back low risk with my last daughter and then she arrived all chromosomally enhanced!

 

[Krissykat1006]

I won't be doing either, with my first child I had a CVS and nothing came back high risk, all scans were normal and when he was born we were surprised to find out he had Down Syndrome! So for me personally I feel what's meant to be will be so I'm just going with that

I thought CVS was a diagnostic test? So it tells you for definite if certain chromosomal anomalies are present or not. Are you sure you had a CVS test last time as they don't normally offer it unless you are high risk?
I know the screening tests are not diagnostic as I too came back low risk with my last daughter and then she arrived all chromosomally enhanced!

Yep!

 

[Disneybaby26]

I'm in prental genetics and process CVS and Amnio samples daily. These tests are definitely diagnostic. Unless your child has a "mosaic" form of Down syndrome or some kind of rare submicroscopic duplication of chromosome 21 which has the possibility of not being detected but still unlikely. I'm interested in the explaination your doctor gave you for the missed diagnosis, if you don't mind me asking?

 

[Krissykat1006]

It was 11 years ago, all I remember from it was him coming in and telling me he double checked everything and nothing showed that he was going to have a chromosomal abnormality. I didn't push for more answers since I was pretty distressed with all the information dumped on me at once including emergency surgery for my child.

 

[HBGirl]

It was 11 years ago, all I remember from it was him coming in and telling me he double checked everything and nothing showed that he was going to have a chromosomal abnormality. I didn't push for more answers since I was pretty distressed with all the information dumped on me at once including emergency surgery for my child.

You do know that a cvs is when you have a needle shoved through your abdominal wall into your placenta and the cells are harvested. They then count the chromosomes in those cells. If your son came back 46XY he would not have had DS.

 

[Krissykat1006]

I do know that.

 

[Krissykat1006]

We had the test done because there was family history of chromosomal abnormalities on my husbands side. Also the test is like 98-99% accurate. It was a high enough accuracy rate that I didn't doubt the results. But like I said things happen for a reason and whats meant to be is meant to be.

This is the last post I am going to make on this. At this point I feel like I am having to prove that I am not full of crap on my results.

 

[joeyjo]

When I was looking into options I did see another post online of a girl whose daughter was born following a clear CVS - she didn't have T21 but did have slight traits similar and the doctors wanted to test the newborn despite the CVS. Apparently there are very rare missed cases, mostly mosaic downs which isn't expressed in the placenta. Things I read pointed to amnio being fractionally more accurate as it tests cells shed from the foetus rather than those expressed in the placenta.

 

[Disneybaby26]

When I was looking into options I did see another post online of a girl whose daughter was born following a clear CVS - she didn't have T21 but did have slight traits similar and the doctors wanted to test the newborn despite the CVS. Apparently there are very rare missed cases, mostly mosaic downs which isn't expressed in the placenta. Things I read pointed to amnio being fractionally more accurate as it tests cells shed from the foetus rather than those expressed in the placenta.

This is absolutely correct.

 

[Disneybaby26]

We had the test done because there was family history of chromosomal abnormalities on my husbands side. Also the test is like 98-99% accurate. It was a high enough accuracy rate that I didn't doubt the results. But like I said things happen for a reason and whats meant to be is meant to be.

This is the last post I am going to make on this. At this point I feel like I am having to prove that I am not full of crap on my results.

I just want you to know that I was in no way questioning your honestly regarding your results. My fear would have been lab or doctor error at retrieval. I have family members with DS, they mean the world to me. My apologies for prying, it was purely professional curiosity about your story.

 

[lm3898]

Just wanted throw out the maternit21 test which is less invasive...I had that done the same day I had my nuchal exam. It's just a simple blood test...no risk of miscarriage etc. which cvs and amnio both carry. The results are back within 2-3 weeks and they are 99% accurate. My doctor told me they do not charge more than $250 no matter what so we felt it was worth it as I have a close family member with chromosomal abnormalities and wanted to be prepared as early as possible.

 

[Eternal]

We had the test done because there was family history of chromosomal abnormalities on my husbands side. Also the test is like 98-99% accurate. It was a high enough accuracy rate that I didn't doubt the results. But like I said things happen for a reason and whats meant to be is meant to be.

This is the last post I am going to make on this. At this point I feel like I am having to prove that I am not full of crap on my results.

Thank you for sharing you're experience, I don't doubt your history, i was surprised as I thought it gave certainly, so it's interesting to know that although rare, it's not 100% (even if it were a case or results being mixed up or something). I've not tested as we would keep whatever the result and I often wonder of I should have just to be prepared, but this made me realise that even if I did everything there is still a chance it could be missed.

The flip side is, my three don't have DS or chromosomal abnormalities but although it's not comparable my eldest had Austin's and ADHD, which isn't something that can be diagnosed before birth.