There is evidence that the exposure of pregnant mice and nonhuman primates to ultrasound waves may affect the behavior of their exposed offspring. Additionally, studies have shown that the frequent exposure of the human fetus to ultrasound waves is associated with a decrease in newborn body weight, an increase in the frequency of left-handedness, and delayed speech.
Because ultrasound energy is a high-frequency mechanical vibration, researchers hypothesized that it might influence the migration of neurons in a developing fetus. Neurons in mammals multiply early in fetal development and then migrate to their final destinations. Any interference or disruption in the process could result in abnormal brain function.
In the study, researchers injected more than 335 fetal mice at embryonic day 16 with special markers to track neuronal development. Exposure to ultrasound waves for 30 minutes or longer caused a small but statistically significant number of neurons to remain scattered within inappropriate cortical layers and in the adjacent white matter. The magnitude of dispersion of labeled neurons was highly variable but increased with duration of exposure to ultrasound waves.
Newnham, J.P., Evans, S.F., Michael, C.A., Stanley, F.J., & Landau, L. I. (1993). Effects of Frequent Ultrasound During Pregnancy: A Randomized Controlled Trial. The Lancet, 342(Oct.9), 887-891.
A study of over 1400 women in Perth, Western Australia compared pregnant mothers who had ultrasound only once during gestation with mothers who had five monthly ultrasounds from 18 weeks to 38 weeks. They found significantly higher intrauterine growth restriction in the intensive ultrasound group. These mothers gave birth to lower weight babies.
The researchers concluded that prenatal ultrasound imaging and Doppler flow exams should be restricted to clinically necessary situations. This recommendation comes at a time when ultrasound during prenatal visits has become increasingly popular and serves as a kind of entertainment feature of office check-up visits.
Campbell, J.D., Elford, R.W. & Brant, R.F. (1993). Case-Controlled Study of Prenatal Ultrasound Exposure in Children with Delayed Speech. Canadian Medical Association Journal, 149(10), 1435-1440.
Delayed speech is not a pathological or organic syndrome but developmentally defined symptom complex. Clinicians have noted an increased incidence of delayed speech in pediatric patients.
This is a matched-case control study of 72 children 2 to 8 years old presenting with delayed speech of unknown cause. The children were measured for articulation, language comprehension, language production, meta-linguisticskills, and verbal memory. When checked for ultrasound exposure, the speech-delayed children were about twice as likely to have been exposed to ultrasound than the matched controls.
The authors believe that delayed speech is a sensitive measure reflecting sub-optimal conditions for development. If ultrasound can cause developmental delays, the authors are concerned about the routine use of ultrasound and they warn against it.
Devi, P.U., Suresh, R., & Hande, M.P. (1995). Effect of fetal exposure to ultrasound on the behavior of the adult mouse. Radiat Res (QMP), 141(3), 314-7.
Pregnant Swiss albino mice were exposed to diagnostic ultrasound. There were significant alterations in behavior in all three exposed groups as revealed by the decreased locomotor and exploratory activity and the increase in the number of trials needed for learning. These results indicate that ultrasound exposure during the early fetal period can impair brain function in the adult mouse.
Hande, M.P., & Devi, P.U. (1995). Teratogenic effects of repeated exposures to X-rays and/or ultrasound in mice. Neurotoxicol Teratol (NAT), 17(2), 179-88.
Pregnant Swiss mice were exposed to ultrasound, x-rays, and combinations of the two. Effects on prenatal development, postnatal growth and adult behavior were studied. U + U group showed an increase in percent growth ******** fetuses. The postnatal mortality was significantly higher only in the U + U group. In the X + U group, the exploratory activity was affected at 6 months of age. There was a significant change in the locomotor activity with a reduction in the total activity as 3 and 6 months of age in the U + U group. Latency in learning capacity was also noticed in this group. The results indicate that repeated exposures to ultrasound or its combination with X-rays could be detrimental to the embryonic development and can impair adult brain function when administered at certain stages of organogenesis.
There are many other studies that have been done, but no one seems to be paying attention to them.