Down's Screening - Been told no point having blood test?

I'm 37 ....will be 38 in a couple of months and my test for Down Syndrome came back 1/465 and 1/10,000 for overall chromosome issues which is a higher chance than in my last pregnancy but still considered low risk! I'm not sure why your doctor told you that......I think it was unprofessional and very uncalled for!!!!
 
I am 38 nearly 39 and had the NT scan and my result never automatically came back high risk - it was 1-3000 x
 
Hi

Just had my first appointment with the midwife and she said there's no point having the blood test to screen for DS because as I'm over 36 it'll automatically come back as high risk. It's the first time I'd heard that. Has everyone else been told that too?

Surely if they're looking at the chemicals in the blood they can still give you a greater or lesser risk within your age category?

Just wondered what other over-36s experience of the screening process has been?


Are you referring to the test that goes withh the NT scan??? I was told the sam thing today by my doctor! Meanwhile my NT measurement was great. He suggested I not bother with the 2nd stage of bloods and go straight to an amnio in 4 weeks..... Im investigating the MaterniT21 blood test....
 
Hun I do prenatal diagnosis and counseling for a living and this is absolutely ludicrous! You bloods and NT will be used to readjust your age-related risk (either decrease it, increase it or have it stay the same). If it is increased you can then opt for additional testing such as amniocentesis to get a definite answer. I'm so sorry you're dealing with a doc who obviously has a very biased view and is trying to impose his/her feelings on the matter onto their patients! :hugs: I would insist on having it done if it is something you want, or request a second opinion!


Hi junebug! I was hoping to find you on here for an opinion.

My doctor today (1st visit) told me that my NT measurement and bloods at my age (42) arent really worth anything because I am automatically high risk and he suggested I go straight to amnio in 4 weeks....
Wouldnt the 2nd stage of bloods, plus my calculations tell me enough? And then the continuous U/S that monitor development??

Also, are you familiar with that new blood test we have here, MaterniT21 ?

I just dont feel good about the amnio, but then again I worry about everything!

How are you doing? Bump getting a little bigger? :)
 
Hun I do prenatal diagnosis and counseling for a living and this is absolutely ludicrous! You bloods and NT will be used to readjust your age-related risk (either decrease it, increase it or have it stay the same). If it is increased you can then opt for additional testing such as amniocentesis to get a definite answer. I'm so sorry you're dealing with a doc who obviously has a very biased view and is trying to impose his/her feelings on the matter onto their patients! :hugs: I would insist on having it done if it is something you want, or request a second opinion!


Hi junebug! I was hoping to find you on here for an opinion.

My doctor today (1st visit) told me that my NT measurement and bloods at my age (42) arent really worth anything because I am automatically high risk and he suggested I go straight to amnio in 4 weeks....
Wouldnt the 2nd stage of bloods, plus my calculations tell me enough? And then the continuous U/S that monitor development??

Also, are you familiar with that new blood test we have here, MaterniT21 ?

I just dont feel good about the amnio, but then again I worry about everything!

How are you doing? Bump getting a little bigger? :)

I just replied to you on the other thread regarding MaterniT21, but if you read my posts in the "Screen Positive for Down" thread, you will see that your doctor might be right, because I was in a similar situation (I am 41, 42 at delivery) and doing the testing caused me a lot of worry untill I got the results back from MaterniT21. You start with the low risk to begin with, around 1:34, so even if your bloods are OK, your risk will improve 4-fold, but it will only get to as high as 1:136 or so, which will keep you wondering still. I did not realize it at the time, so I went for the combined screening only to be disappointed since it went down 4-fold to 1:9, just because the blood markers were slightly off in the wrong direction. In the end I am glad I did it, because I would have not found out about MaterniT21 otherwise. Plus I had a chance to see the U/S findings that kept me reassured while waiting for the results, because the U/S is more reliable than the combined screening, which I also address in my other post. In your case, if you want to avoid the amnio, go straight for MaterniT21, if you can afford it, - it is as reliable as the amnio, or even more so, can be done as early as 10 weeks and is non-invasive.
 
Hi Helenita...
Where in the usa are you? It isnt yet offered in NY, and I am going to see if it is available in NJ or even CT and if insurance will cover it. i can handle the $200, but not $2,000....

Thanks!
 
Hi Helenita...
Where in the usa are you? It isnt yet offered in NY, and I am going to see if it is available in NJ or even CT and if insurance will cover it. i can handle the $200, but not $2,000....

Thanks!

Hi Sadie,
I am currently in Tucson, AZ, but had to go to Phoenix, AZ, to do the test. I was told it is only available in 40 labs around the US, but they did not tell me which ones. :-( If I find out, I will let you know. I am surprised that they don't have it in NY, unless you mean the state and not the NYC. It may be available in NYC and the cities of that size. (i.e. Phoenix, LA, etc.)
 
NYS has not yet approved it tho the company has applied for it to be in NY.... I wonder if insurance would pay for it, if I go to another state....

In any case, do you know what your NT measurement was? Mine was 1.80 mm which was great njust waiting on the bloods, but doc made it seem useless to even look at the data.
 
NYS has not yet approved it tho the company has applied for it to be in NY.... I wonder if insurance would pay for it, if I go to another state....

In any case, do you know what your NT measurement was? Mine was 1.80 mm which was great njust waiting on the bloods, but doc made it seem useless to even look at the data.

Like I said before, your doctor might be right. I have come to this conclusion after finding some information on the net that I posted on another thread and I am quoting it again here to clarify what I mean.

As I was researching the Internet on the subject of the 1st trimester screening, I have come across the forum discussing the same issue and read the answer of a pregnant woman who was also a Statistician. I am posting part of her answer (most relevant) below. She was replying to another lady who was worried about getting the high risk for the Down syndrome (1:47) based on her combined NT/blood testing. I found her explanation interesting and perhaps it will also help any of you understand things about prenatal screening.

"...I'm answering you as both, as a statistician and as a mother. Statistician's voice: The way the ''nuchal test'' is typically conducted in medical practices in the US these days is an unfortunate marriage between a relatively reliable and a very unprecise indicator. I can not see how these two very different things can, even half-resonably, be combined into one likelyhood:
(A) The measurement of the nucal fold taken during an ultrasound. If the measurement is above a certain threshold (2.5 if I remember well), this is a semi-quantitative (but relatively reliable) indicator for Down syndrome.

(B) A measurement of the concentration of a hormones released in pregnancy, and some other data. It has been observed that the concentrations of this hormon develop slightly differently when the fetus has Down syndrome (or other chromosomal problems, or spina bifida). A deviation from the typical curve can, but does not have to, be caused by Down syndrome or one of the other diseases. Unfortunately, the evaluation of the results is extremly sensitive to the estimated time of conception. The latter is estimated by the date of last period, or by ultrasound. Both methods are not precise enough to ensure the interpretation is even half reasonable.

I would encourage doctors to report their findings separately. Every woman who chooses to do this test should be reported the measurement from (A). She could then choose by herself if she wants to put any confidence in part (B) or not. In particular, if she already has reasons to belief that the date of conception (the doctors will talk about ''due date'' for the birth, actually) was well estimated. For example, if her cycle lengths are not the ''normal'' 28 days, if she's not sure about her date of last period, or if the dates based on the day of last period and the date based on ultrasound differ. I actually talked to the statistician in charge of the Californian program for screening for genetical diseases. He said that something like three days off the correct date of conception can completely falsify the results. Doctors and their assistents usually do not even know this, and go ahead to do a useless computation. The results they report to the women are probabilities of a precision that is misleading. I would like to see the standard errors for their computations. It would not be surprising to see: ''the probability your fetus has Down syndrome is, most likely, some number between 1/10 and 1/300''. What are you making out of this information?..."

And just to prove the point above and to answer your question, my NT measurements were 2.3 and 1.8 at 12w and 13w6d respectively, my combined risk came back as 1:9, but the baby is normal, as confirmed by MaterniT21. So, as you can see the U/S is a better predictor of the reality, but for those who need to know for sure, the diagnostic test of some sort will still be necessary.
 
I also found this site that does a good job explaining how they calculate the risk of Down syndrome:

https://www.wolfson.qmul.ac.uk/epm/screening/calcrisk.html

However, yet again, by looking at the graphs there, you can see that the values of the blood markers for a healthy baby and a baby with Down syndrome overlap so much that even a "bad" MoM value can still fall within a normal range, making it a very unreliable indicator.
 
Thanks for the info.

I am going to try t o find where the blood test is offered and if insurance will cover me if i go out of state for it.
 
I don't think it matters where you do the test, because the billing is done through the headquarters in San Diego and since they only offer it in limited places,I would imagine people often will need to travel out of state to do the test. Also, with or without insurance you will only pay $235 from what I understand, but I may be wrong, or maybe if insurance denies the payment, you will still only pay $235, so if you have insurance that is a PPO plan, you should not worry.
 
It is offered in Nj and the only way to have it done is for a NJ doctor to prescribe it, so I am in the process of searching for doc in NJ that will offer me a consult so that they can provide me with the blood test order..... So ridiculous that a NY doc cant order it for me.
 

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