Found Out The Problem!
- Thread starter beth30
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fumbles
Pregnant and terrified!
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Sorry to hear that! I guess in some ways it's good because you know there is something wrong, it has a name, and there are ways to deal with it. On the other hand it sucks having a problem at all!
I think it means you are more likely to suffer from a m/c as you have an increased risk of neural tube defects? Might be worth having a good look around to see if there are any support groups, they will be better at giving you a prognosis.
I think it means you are more likely to suffer from a m/c as you have an increased risk of neural tube defects? Might be worth having a good look around to see if there are any support groups, they will be better at giving you a prognosis.
beth30
2 Rainbow Boys and Preggo
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Methylenetetrahydrofolate reductase (MTHFR) is a rare genetic defect that can lead to complications in pregnancy. Many people do not know that they have this defective gene until after they have had several unsuccessful pregnancies. Others may carry one pregnancy to term and not discover until afterwards that they carry the defect.
What is MTHFR?
Methylenetetrahydrofolate reductase (MTHFR) is the name of a gene that produces an enzyme, also called methylenetetrahydrofolate reductase. If a person carries the genetic mutation that inhibits production of this enzyme, it can result in hyperhomocytenemia, which is an elevated level of an enzyme called homocysteine found in blood plasma.
When the body is deficient in methylenetetrahydrofolate reductase, its ability to absorb folate (also known as vitamin B9), such as folic acid, is inhibited. Folic acid and B9 are both essential to the development and health of the fetus.
MTHFR and Pregnancy
Because of a mother with MTHFR’s inability to efficiently metabolize folic acid and vitamin B9, the disorder has been linked to a variety of pregnancy complications such as chromosomal abnormalities, such as Down syndrome, and congenital malformations.
Elevated levels of homocysteine have been associated with placental disease, preeclampsia and recurrent pregnancy loss. 21% of women with high levels of homocysteine experience recurrent pregnancy loss.
Symptoms
Because MTHFR is a blood-based disease with many varieties, symptoms vary depending on the exact mutation of the disease. They can include:
•blood clots
•depression
•anxiety
Detection
Blood testing is the most accurate way to screen for MTHFR. This is especially true if women have a history of complicated pregnancies, including recurrent pregnancy loss and/or stillbirths, or if they have given birth to a child with neural tube defects, such as spina bifida.
Treatment
Taking folic acid can help women with certain mutations of the disease. Folic acid can be found in eggs, dark leafy vegetables, such as spinach and broccoli, oranges and orange juice and legumes, such as peas and dried beans. Vitamin supplements also contain folic acid.
What is MTHFR?
Methylenetetrahydrofolate reductase (MTHFR) is the name of a gene that produces an enzyme, also called methylenetetrahydrofolate reductase. If a person carries the genetic mutation that inhibits production of this enzyme, it can result in hyperhomocytenemia, which is an elevated level of an enzyme called homocysteine found in blood plasma.
When the body is deficient in methylenetetrahydrofolate reductase, its ability to absorb folate (also known as vitamin B9), such as folic acid, is inhibited. Folic acid and B9 are both essential to the development and health of the fetus.
MTHFR and Pregnancy
Because of a mother with MTHFR’s inability to efficiently metabolize folic acid and vitamin B9, the disorder has been linked to a variety of pregnancy complications such as chromosomal abnormalities, such as Down syndrome, and congenital malformations.
Elevated levels of homocysteine have been associated with placental disease, preeclampsia and recurrent pregnancy loss. 21% of women with high levels of homocysteine experience recurrent pregnancy loss.
Symptoms
Because MTHFR is a blood-based disease with many varieties, symptoms vary depending on the exact mutation of the disease. They can include:
•blood clots
•depression
•anxiety
Detection
Blood testing is the most accurate way to screen for MTHFR. This is especially true if women have a history of complicated pregnancies, including recurrent pregnancy loss and/or stillbirths, or if they have given birth to a child with neural tube defects, such as spina bifida.
Treatment
Taking folic acid can help women with certain mutations of the disease. Folic acid can be found in eggs, dark leafy vegetables, such as spinach and broccoli, oranges and orange juice and legumes, such as peas and dried beans. Vitamin supplements also contain folic acid.
beth30
2 Rainbow Boys and Preggo
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Yeah, I'm okay. Thanks. I'm am more relieved than anything, because atleast now I know what it wrong! I just kept telling everyone in my circle that something was wrong, and they acted like I was the neighborhood nut job.... I am so happy that I am getting some validation! Sucks I have this, but glad I know about having, and can take control!
Holly TH
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Beth,
I admire the proactive approach you are taking to educating yourself about MTHFR. I work with NeevoDHA, a prenatal indicated for women with the MTHFR polymorphism. Maybe I can help. MTHFR polymorphism is a genetic mutation which inhibits your ability to metabolize folic acid into L-methylfolate. NeevoDHA contains L-methylfolate, the active form of folate which bypasses the MTHFR polymorphism. It is 7 times more bioavailable than folic acid. L-methylfolate also increases folate levels and decreases homocysteine levels more effectively than folic acid. Folate is vital while trying to conceive and during pregnancy due to its role in DNA repair and synthesis.
I hope this answers some of your questions. I wish you the best of luck.
I admire the proactive approach you are taking to educating yourself about MTHFR. I work with NeevoDHA, a prenatal indicated for women with the MTHFR polymorphism. Maybe I can help. MTHFR polymorphism is a genetic mutation which inhibits your ability to metabolize folic acid into L-methylfolate. NeevoDHA contains L-methylfolate, the active form of folate which bypasses the MTHFR polymorphism. It is 7 times more bioavailable than folic acid. L-methylfolate also increases folate levels and decreases homocysteine levels more effectively than folic acid. Folate is vital while trying to conceive and during pregnancy due to its role in DNA repair and synthesis.
I hope this answers some of your questions. I wish you the best of luck.
Holly TH
Active Member
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Beth,
I admire the proactive approach you are taking to educating yourself about MTHFR. I work with NeevoDHA, a prenatal indicated for women with the MTHFR polymorphism. Maybe I can help. MTHFR polymorphism is a genetic mutation which inhibits your ability to metabolize folic acid into L-methylfolate. NeevoDHA contains L-methylfolate, the active form of folate which bypasses the MTHFR polymorphism. It is 7 times more bioavailable than folic acid. L-methylfolate also increases folate levels and decreases homocysteine levels more effectively than folic acid. Folate is vital while trying to conceive and during pregnancy due to its role in DNA repair and synthesis.
I hope this answers some of your questions. I wish you the best of luck.
I admire the proactive approach you are taking to educating yourself about MTHFR. I work with NeevoDHA, a prenatal indicated for women with the MTHFR polymorphism. Maybe I can help. MTHFR polymorphism is a genetic mutation which inhibits your ability to metabolize folic acid into L-methylfolate. NeevoDHA contains L-methylfolate, the active form of folate which bypasses the MTHFR polymorphism. It is 7 times more bioavailable than folic acid. L-methylfolate also increases folate levels and decreases homocysteine levels more effectively than folic acid. Folate is vital while trying to conceive and during pregnancy due to its role in DNA repair and synthesis.
I hope this answers some of your questions. I wish you the best of luck.
