Unfortunately it seems like most of the legitimate "work-from home" opportunities are direct sales, like trunk-show type parties where you invite your friends and sell them candles, jewelry, cosmetics, adult novelties, etc. They might be good for a quick buck but in the long run, unless you are really a great networker and salesperson, you will run out of friends to sell to. Legitimate companies I know of personally include PartyLite (candles), Scentsy (wickless candles), Premier Designs (jewelry), Lia Sophia (jewelry), Avon (cosmetics), Mary Kay (cosmetics), Tupperware (storage products), Herbalife (nutritional products), Longaberger (home products), and Pampered Chef (cooking products). Here is a list of more companies like this if you are interested: https://www.theworkathomewoman.com/direct-sales/
Most people I know (including myself) who work from home perform some sort of service that they can do as a freelancer, or already have a relationship with an employer that has allowed them to work from home part or full time. I do writing and graphic design, but I know others who do bookkeeping, billing, and other things. However I worked in the field for 10 years and made lots of professional contacts before being able to do this.
If you are crafty or have an eye for finding garage sale bargains, you could always open an Etsy shop, although it would take some time to get "popular," if you offer something people want and are willing to pay for, it could take off. Or maybe you could offer an eBay listing service where people pay you a percentage to to photograph, list, and ship their items. Once again it will depend on your ability to network and find people willing to pay you. But it can be done if you are persistent.