-
Xenforo Cloud upgraded our forum to XenForo version 2.3.4. This update has created styling issues to our current templates. We will continue to work on clearing up these issues for the next few days, but please report any other issues you may experience so we can look into. Thanks for your patience and understanding.
LUF cycles
- Thread starter Clueless
- Start date
Kelly9
Well-Known Member
- Joined
- Mar 8, 2009
- Messages
- 33,267
- Reaction score
- 0
LUFS (luteinized unruptured follicle syndrome) is a fertility issue where if you chart you don't ovulate but you still get your temp spike and all that jazz, I believe in people that have it there are typically no symptoms. The follicle will grow but will not be released by the ovary. Thats about all I know about it though... some doctors believe that such a syndrome doesn't exist maybe cause there is no way to tell for sure if someone has it? Good luck!
maz
TTC #1 since Oct 2004
- Joined
- Feb 16, 2008
- Messages
- 3,887
- Reaction score
- 0
Never heard of it, but from what Kelly9 says I'd imagine the only way of knowing for sure that you've released an egg would be through US. After ovulation, the fluid that was in the follicle before the egg was released, should be visible in the abdominal cavity apparently. The reason I say this, is because I was paranoid at my first IVF cycle that I had already OVd, but the nurses were able to say that there was no fluid in my abdomen so I definitely hadn't.
Who suggested to you that you may have LUF?
Who suggested to you that you may have LUF?
Clueless
Mom
- Joined
- Mar 9, 2009
- Messages
- 2,187
- Reaction score
- 0
It was suggested by the doctor who did the confirmation scan for my miscarriage. I explained it had taken three and a half years to get this far and what treatment we'd had. He said that my clomid cycles should have been tracked by ultrasound and maybe I should have had injectable meds along with these cycles.
He wrote a letter to my GP immediately and suggested, without actually saying so, not to remind my GP what treatment I had already had so he'd refer me. Luckily my GP was very happy to do so.
I temp and my last 2 CD21 tests show that I am ovulating, but after what he has told me, how can anyone be sure without further investigation? Hopefully I will get to know for sure soon enough and maybe something can be done about it?
He wrote a letter to my GP immediately and suggested, without actually saying so, not to remind my GP what treatment I had already had so he'd refer me. Luckily my GP was very happy to do so.
I temp and my last 2 CD21 tests show that I am ovulating, but after what he has told me, how can anyone be sure without further investigation? Hopefully I will get to know for sure soon enough and maybe something can be done about it?
I would imagine that all the hormones act exactly as they should, giving you perfect cycles and the right levels at the right time, but on a structural level the follicle doesnt burst in response to the LH surge. The strange part is that its the corpus luteum, basically the empty follicle, that is supposed to be the reason for the progesterone rise... be very interested to hear more about this when you know more 
unless you are monitored by ultrasound, you'll never be certain...
unless you are monitored by ultrasound, you'll never be certain...
Clueless
Mom
- Joined
- Mar 9, 2009
- Messages
- 2,187
- Reaction score
- 0
I've nicked this from medscape.com
"""Part of an infertility evaluation is the documentation of ovulation. When a woman has regular cycles, in 95% of cases it is the sign of regular ovulation. Most tests that are used to document ovulation do not actually confirm the oocyte release but document only the hormonal changes. The measurement of basal body temperature, changes in the cervical mucus, measurement of luteal phase progesterone level, and secretory changes as indicated by endometrial biopsy all reflect an increased progesterone production.
The actual rupture of the follicle and the release of the oocyte can be demonstrated during laparoscopy. Serial ultrasound studies can also be used to follow the growth of the follicle and its collapse following ovulation.
In a small percentage of women, the dominant follicle will undergo the luteinization process without rupture following the midcycle surge. As a result of the increased progesterone secretion, the endometrium undergoes the secretory changes, but, obviously, without the release of the oocyte pregnancy cannot occur. Hormonal studies, the basal body temperature curve, and the findings in an endometrial biopsy will all be consistent with ovulation. The cycles will follow each other regularly. This phenomenon is called the luteinized unruptured follicle (LUF). According to some studies, LUF is more common among women with endometriosis. Others question the existence of LUF. Laparoscopy has been used to check for ovulatory changes in the ovaries and therefore to establish the diagnosis of LUF. More recently, ultrasound monitoring with serial scans has replaced laparoscopy in the diagnostic process. The lack of follicle rupture and the lack of free peritoneal fluid around the time of ovulation are used to establish the diagnosis of LUF.
If ovulation does not occur on its own, hormonal induction may be attempted. Human chorionic gonadotropin (hCG) in doses of 5000-10,000 IU intramuscularly, or, more recently, 250 micrograms subcutaneously, can be administered to induce ovulation. When the lead follicle reaches 18-20 mm in diameter, the injection can be given. It takes about 36 to 40 hours for the oocyte to be released after the injection. Intercourse or insemination should be timed accordingly. Ultrasound can be used to document ovulation. If it still does not take place, the dose of the hCG injection can be increased. If ovulation still cannot be achieved even with the hCG injection, in vitro fertilization with the retrieval of oocytes could become the ultimate solution, but it seems to be a rather drastic step in the management of LUF."""
Still trying to work out why the progesterone still rises...
"""Part of an infertility evaluation is the documentation of ovulation. When a woman has regular cycles, in 95% of cases it is the sign of regular ovulation. Most tests that are used to document ovulation do not actually confirm the oocyte release but document only the hormonal changes. The measurement of basal body temperature, changes in the cervical mucus, measurement of luteal phase progesterone level, and secretory changes as indicated by endometrial biopsy all reflect an increased progesterone production.
The actual rupture of the follicle and the release of the oocyte can be demonstrated during laparoscopy. Serial ultrasound studies can also be used to follow the growth of the follicle and its collapse following ovulation.
In a small percentage of women, the dominant follicle will undergo the luteinization process without rupture following the midcycle surge. As a result of the increased progesterone secretion, the endometrium undergoes the secretory changes, but, obviously, without the release of the oocyte pregnancy cannot occur. Hormonal studies, the basal body temperature curve, and the findings in an endometrial biopsy will all be consistent with ovulation. The cycles will follow each other regularly. This phenomenon is called the luteinized unruptured follicle (LUF). According to some studies, LUF is more common among women with endometriosis. Others question the existence of LUF. Laparoscopy has been used to check for ovulatory changes in the ovaries and therefore to establish the diagnosis of LUF. More recently, ultrasound monitoring with serial scans has replaced laparoscopy in the diagnostic process. The lack of follicle rupture and the lack of free peritoneal fluid around the time of ovulation are used to establish the diagnosis of LUF.
If ovulation does not occur on its own, hormonal induction may be attempted. Human chorionic gonadotropin (hCG) in doses of 5000-10,000 IU intramuscularly, or, more recently, 250 micrograms subcutaneously, can be administered to induce ovulation. When the lead follicle reaches 18-20 mm in diameter, the injection can be given. It takes about 36 to 40 hours for the oocyte to be released after the injection. Intercourse or insemination should be timed accordingly. Ultrasound can be used to document ovulation. If it still does not take place, the dose of the hCG injection can be increased. If ovulation still cannot be achieved even with the hCG injection, in vitro fertilization with the retrieval of oocytes could become the ultimate solution, but it seems to be a rather drastic step in the management of LUF."""
Still trying to work out why the progesterone still rises...
Clueless
Mom
- Joined
- Mar 9, 2009
- Messages
- 2,187
- Reaction score
- 0
Listen to this...
"""LUF is seen in 10% of menstrual cycles of normal fertile women (Killick and Elstein, 1987). A higher incidence has been reported in infertile women (Marik and Hulka, 1978). The occurrence of LUF has been linked to many conditions such as unexplained infertility, endometriosis, pelvic adhesions and the use of non-steroidal anti-inflammatory drugs (NSAIDs) (Marik and Hulka, 1978; Katz, 1988; Akil et al., 1996). LUF has been demonstrated in both spontaneous and stimulated cycles (Craft et al., 1980)."""
Nicked from humrep.oxfordjournals.org
"""LUF is seen in 10% of menstrual cycles of normal fertile women (Killick and Elstein, 1987). A higher incidence has been reported in infertile women (Marik and Hulka, 1978). The occurrence of LUF has been linked to many conditions such as unexplained infertility, endometriosis, pelvic adhesions and the use of non-steroidal anti-inflammatory drugs (NSAIDs) (Marik and Hulka, 1978; Katz, 1988; Akil et al., 1996). LUF has been demonstrated in both spontaneous and stimulated cycles (Craft et al., 1980)."""
Nicked from humrep.oxfordjournals.org
That is very interesting hon... as to why the progesterone is still produced, could that simply be in response to the LH surge? hcg mimics the lh surge, which is why in pregnancy hcg is produced to maintain progesterone production from the corpus luteum until the placenta takes over?
Similar threads
Users who are viewing this thread
Latest posts
-
-
General chatter while we wait (and commentary on the "pull out method") (1 Viewer)- Latest: gigglebox
-
-
