i make up 24hrs in advance. I generally feed on demand, but its every 3hrs during the day.. It depends what time he wakes up, for example if he wakes up at 6 his feeds go, 6,9,12,3,6,9 sleep thru, but then might not wake up till 8 then it would go, 8,11,2,5,8. Some days he will have 6bottles some days 5, but he never has a bottle later than 10pm otherwise hes up every 3hrs during the night too! X