I've taken it and I csn't say it made the slightest bit of difference to any of my symptoms, buscopan was slightly better but the best IBS med i've had is Spasmonal, (not sure on the spelling) If this is the first time you've had IBS meds it can be a bit of trial and error to find the right medication to help. As best I remember being told though you should start noticing a difference in a week or so.