You need to check with a doctor really, or a pharmacist. I think there are some histamines that are OK during pregnancy, but not decongestants. Every time I went for advice at different chemists/pharmacies when I had colds and sinus trouble, they couldn't find anything that could help me. It was a case of steaming with olbas oil/friars balsam to loosen everything up then just trying to blow it all out. Paracetamol to help with the sinus pain. I know, it's horrible isn't it!?