MTHFR Questions

[Girlnextdoor]

Hey all! I just got a call from my RE and she said that I have the mutation for MTHFR. Are there any of you that have tested positive for this? What kind of treatment did you have to get? And any successful pregnancies afterward? Thanks for all the info!

I hope that this will be helpful for me to carry a successful pregnancy. It sucks to hear that something is wrong, but when she told me I just started crying because I was so relieved to have found SOMETHING. She is putting me on prescription strength B vitamins and baby asprin, and I will have to do "injections" (heparin?) once I am pregnant.

 

[JulianasMommy]

What is this???

 

[MRS_HJO]

I'm following this thread. What is MTHFR??? What does it mean for you?

I'm not glad something is wrong, but I'm glad you finally have an answer.

 

[MRS_HJO]

Reading online it causes neural tube defects. Very glad your doctor has found this.

 

[Girlnextdoor]

Well, I don't really understand it yet. I just found out and am starting to research it. I will post more when I find more info. But, from what the nurse explained to me, it is a genetic mutation that causes blood clotting problems.

As far as what it means for me, I obviously have an increased risk of mc All I know so far is that it does something so that your body cannot properly convert folic acid, hence the reason for extra B vitamins. Also, I think it causes problems with blood clotting around the placenta, which is why I would take the asprin and the injections. That is all I know so far. I am going to keep researching, and I will meet with the RE in a couple of weeks so hopefully she can explain it some more.

 

[Girlnextdoor]

Reading online it causes neural tube defects. Very glad your doctor has found this.

Yes, I also saw that it can cause health issue such as clogged arteries, eeek! It seems to be fairly common. I thank God that I had a healthy baby already because everything I am reading is scary. I am so lucky for him.

It makes sense to me that there is a higher risk for neural tube defects, since your body cannot properly use the folic acid.

 

[JPARR01]

I am glad that you finally have an answer.

 

[MRS_HJO]

Okay, I just spoke to my SIL because this sounded like what she has, and yes, she has the SAME THING. She had to give herself injections in her tummy while she was TTC and while she was pregnant to keep her blood thin. This is something she was born with. She has never had a m/c and has two healthy daughters, but after childbirth, both times, she developed a severe blood clot and was hospitalized. Not saying that will happen to you, but something about her being pregnant, it makes the blood clotting issue act up.

 

[Girlnextdoor]

Thanks for checking with your SIL, Heather. It is good to know that she delivered two babies! I am hopeful that my next pregnancy will work with treatment.

 

[wishing4bub#3]

hi I have a single fault and hubby has a doubble. i just need to increase my folate and B12 intake. i was diagnosed over a year ago and i the only thing they do for me is monitor m homosysteine levels. as a change in thi means current meds and diet are not working.

the way it was explained to me is that 1 in 3 have a single fault especialy if they are of an european background. it also cause problems with the placenta. i always seam to miscarry at 6 weeks and 4 days.

i hope this helps a little as the cours of action from your specialist will depend on other hormones in your body. as one thing interacts with the other so chances are you wil need more blood testing for a better picture of what is goin on.

good luck
i also have other issues that why i have a high MC rate and have been ttc for a while now.

 

[diane60f]

I have a compound heterozygous mutation on my C and A gene. 4 miscarriages then did testing....and then finally my rainbow baby perfectly healthy. Was on vit b6 and b12 and 5mg folic acid and 81g aspirin.

Feel free to pm me

Don't be afraid of this.
Have your doc check your homosyctiene levels. That's what's important. The mutations are fairly common.

 

[Girlnextdoor]

hi I have a single fault and hubby has a doubble. i just need to increase my folate and B12 intake. i was diagnosed over a year ago and i the only thing they do for me is monitor m homosysteine levels. as a change in thi means current meds and diet are not working.

the way it was explained to me is that 1 in 3 have a single fault especialy if they are of an european background. it also cause problems with the placenta. i always seam to miscarry at 6 weeks and 4 days.

i hope this helps a little as the cours of action from your specialist will depend on other hormones in your body. as one thing interacts with the other so chances are you wil need more blood testing for a better picture of what is goin on.

good luck
i also have other issues that why i have a high MC rate and have been ttc for a while now.

thanks so much for the information! i am so sorry for all of your losses. that must be so painful for you to have to go through i hope you get your forever baby very soon.

 

[Girlnextdoor]

I have a compound heterozygous mutation on my C and A gene. 4 miscarriages then did testing....and then finally my rainbow baby perfectly healthy. Was on vit b6 and b12 and 5mg folic acid and 81g aspirin.

Feel free to pm me

Don't be afraid of this.
Have your doc check your homosyctiene levels. That's what's important. The mutations are fairly common.

thanks, diane. i have no idea if she has checked me homocysteine levels or not yet. i will find out more later, i guess. all i know is that she wants me to do the prescription b vitamins and aspirin, and then injections after bfp.

i am nervous, but actually less nervous than i was before when i didn't know anything about what was going on. i really hope this is the answer for me.

your baby is precious, congratulations! i am so happy you were able to overcome all the mc and go on to have a healthy pregnancy.

 

[Pebbles80]

I also am positive for the MTHFR gene mutation. I think I'm just heterozygous for it, so its only half-bad. My RE put me on a high dose folic acid/vit b combo. He kind of acted like it wouldn't be a problem if I just took the prescription strength folic acid daily. I also have other issues, which I think may have contributed to the miscarriages (luteal phase defect issues and a bicornuate uterus). Good luck!