Recurrent Miscarriage Thread

[petitpas]

My (nkcells) consultant routinely prescribes progesterone to everyone as far as I can see (his treatment plans are online). I believe this is because progesterone suppresses the immune system a little. That's why, weirdly, us womenfolk are more likely to catch a cold in the second part of our cycle. So, as far as I can see (I'm not a bio or medical professional, mind) progesterone has two advantages. It thickens the lining of the uterus and it suppresses the immune system so an implanting embryo is less likely to be seen as a threat to the body.
I also toyed with not taking it at some point as I didn't know whether I really needed it but ultimately, it isn't supposed to be harmful and I would rather carry a doomed pregnancy a few days longer if necessary than lose a healthy bean that might just have survived had I taken the progesterone. Those are just my personal thoughts on it. As I said, I am no medical professional and there is probably some truth in the fact that a lot of us end up overmedicated
Ultimately, everyone needs to be comfortable with their own personal treatment regime and what might be acceptable to me might be way overkill for someone else.

 

[Lou2307]

Petitpas... I suppose I never looked at it that way. Aye it won't do no harm and might actually help. Prob just a coincidence that when I've used them nothing much ever developed...
When I was using them from ovulation I couldn't get pg then as soon as I stopped them I got pg. still didn't workout tho... Then again I'm slowly but surely coming to the conclusion that no matter what I do it won't work.

So I got an email from my consultant last night offering her condolences as my pregnancy has failed.. A nice touch I thought.
She is only back after a holiday and when I emailed her back I got an out of office reply she's off again... Another holiday.. Jeez how many holidays do they get��

Anyway I wrote her a big story how I think it's time I moved on to another doctor as I've been seeing her for 7 years and still haven't been successful. I asked her if she can refer me to mr shehata through NHS. She's very skeptical about him and doesn't agree with some of his treatments so I don't know what she will do.
Surely she would as the ultimate goal is to have a successful pregnancy.

Failing that I've Also asked to be referred to st Mary's for this teg test that only they do.. Fingers crossed she plays nice and just does it for me. She's not back in till next tues so I hope to hear from her when she gets back.
I was going to wait until she sent me out an rmc appointment but that could take ages. So I just thought while I have her direct email just to use it.

I've also sent a letter via email to prof quenby to see if she would have any advise for me as I've now had 2 losses... Albeit very early.. Under their treatment plan.

I'm down but I'm not gonna be beaten x

 

[ttcbabyisom]

I just wanted to say hi to everyone here and give everyone a great big HUG! I'm saying a prayer that you all leave this thread, get pregnant and have your forever babies soon! NO MORE LOSSES!

 

[petitpas]

Lou, you're doing great with your fight! I went to St Mary's and then when I had exhausted all their options I moved on to Mr S as well. Don't get me wrong, St Mary's is really good, it's just that ultimately, I needed more and Mr S's steroids did the trick.

 

[TTC First]

I have been trying to get PG for like 2 years now. I can't get PG on my own but I can get PG with IUI. The problem is that I keep loosing the babies (three in total). I have done every test that there is an everything is fine.

I would think that this is unexplained infertility however I am able to get
pregnant.

It's one thing not to be able to get pregnant and it's another to have a medical condition that effects pregnancy. But, its just cruel punishment to be able to get pregnant but have each baby not make it.

Even an IVF wouldn't help me in this situation.

Is there anyone out there that is in the same position?

The doctor said that I could keep trying and decide when I wanted to stop. If I was able to get pg on my own I wouldn't mind trying long term, but when you have to pay for an IUI that's a different situation.

 

[Tasha]

Firstly Have you been tested for natural killer cells? Did you have steroids whilst having your iui?

 

[TTC First]

Firstly Have you been tested for natural killer cells? Did you have steroids whilst having your iui?

Hi Tasha

I have never hear of "natural killer cells", is that the medical term? I will look into that. No I was not on any medication during my IUI (except progesterone).

I just looked it up and it seems that its quite expensive to get tested for natural killer cells in Canada.

 

[ginny83]

The other thing to consider is have any of your losses been tested? Sorry to hear what you have been going through. There are a couple of ladies on here who also have issues fallibg pg as well as rm. So extra unfair

 

[ginny83]

How are you going tash? x

 

[mowat]

I'm in Canada as well TTC and I asked at my fertility clinic about getting tested for NK cells and they said it could happen, but would be extremely expensive. Not sure how much that was, but as I have to fly ($500 minimum) just to get to my clinic I decided to have one more try without testing. I emailed various places in the US about the testing, but never heard back from anyone. Additionally, I don't think there was any way I could get the blood samples to them quickly enough.

I've had multiple unexplained losses, and this time I did IVF. For whatever reason it seems to be sticking so far (still early days). I'm currently on estrogen, progesterone, aspirin, D, folic, multivitamin and prednisone.

 

[ginny83]

If you're on prednisone you're basically taking the treatment for high NK cells anyway

 

[Hope39]

Firstly Have you been tested for natural killer cells? Did you have steroids whilst having your iui?

Hi Tasha

I have never hear of "natural killer cells", is that the medical term? I will look into that. No I was not on any medication during my IUI (except progesterone).

I just looked it up and it seems that its quite expensive to get tested for natural killer cells in Canada.

The blood test can be cheap if you sort if yourself, I have come across ladies that sent their blood sample direct by FedEx to America, it's the franklin Rosalind university that do the level 11 chicago immune testing

Your problem would then be getting the results interpreted . Fertility friend has quite a lot of info on this

Xx

 

[dan-o]

Hi ladies sorry to butt in.. But has anyone here heard of thalassemia? Or been affected by it?

Had a heads up on the genetic testing from our last loss and this has popped up, they've recommended a full genetic work up for both myself and my husband. From what I gather this may affect ourselves, our two living children as well as explaining some of our losses. We have a consultation on 26th but a very helpful miscarrige clinic nurse is trying to get me some more info before then.

 

[ginny83]

I've never heard of it before Dan-O.... just googled it then, how did they pick it up? Was it from a blood panel on you?

 

[ginny83]

Besides my 16 week loss, when ever they tested the baby they only looked at the number of chromosomes nothing else, so that's impressive if they're really looking at other medical factors in the baby

 

[dan-o]

No just from the baby. I've not had my RMC bloods done yet, still waiting for that. Who knows what else that will uncover, it's like a can of worms lol!!!

 

[ginny83]

wow, that's pretty good they picked that up. I was told that genetic testing was just testing on the chromosomes here - unless when they look at the chromosomes they also can't help but look at the blood cells if that makes sense.

Will they test to see if you and DH are carriers? or could it be just a random once off occurrence?

 

[dan-o]

That crossed my mind also, perhaps it was just noticed iykwim.
From what I gather, via google, either one or possibly both of us will have it. Yikes!

 

[TTC First]

The other thing to consider is have any of your losses been tested? Sorry to hear what you have been going through. There are a couple of ladies on here who also have issues fallibg pg as well as rm. So extra unfair

I was so excited with the last loss (if you can say that) because they said that they were going to test the "product". Well I took it to the hospital and they said that there was no fetal material (I believe that's what they called it). So that test was a wash. This was the third loss so I was really upset that they were not able to test.

 

[TTC First]

I'm in Canada as well TTC and I asked at my fertility clinic about getting tested for NK cells and they said it could happen, but would be extremely expensive. Not sure how much that was, but as I have to fly ($500 minimum) just to get to my clinic I decided to have one more try without testing. I emailed various places in the US about the testing, but never heard back from anyone. Additionally, I don't think there was any way I could get the blood samples to them quickly enough.

I've had multiple unexplained losses, and this time I did IVF. For whatever reason it seems to be sticking so far (still early days). I'm currently on estrogen, progesterone, aspirin, D, folic, multivitamin and prednisone.

Very interesting. Have you always been on those medications?

It seems that someone had a follow up to your post saying that prednisone is a treatment for NK. Is that why it was prescribed? I am tinkling that I may ask for some too.

My doctor said that in my case IVF would not give a different outcome. Maybe in your case it's the medication so I would love to try that too.

How far along are you?

All the best and hoping for a HH 9 months!!!!!!!!!!!!