Here are my thoughts:
1. It's really hard on the body: I worried about this, but then read tht a lot of women who have trouble with Clomid don't have trouble with IVF meds, and I had a HORRIBLE time on Clomid and Femara. Ended up bedridden off and on for months, had to quit my job, ended up with severe depression, was sick and in pain constantly, hot flashed galore. Couldn't sleep, puking all the time. It was AWFUL. IVF has been easy for me.
For IVF, I've just finished all my injections. The Gonal-F gave me practically no side effects and I've felt pretty much great the whole time. I had one bout of nausea with my trigger last night, but that has been the only physical side effect, besides slightly sore bb's during stims. Mentally, I'm doing much better as well, a little grouchy at times, but not the emotional wreck I was on Clomid/Femara. I don't even feel any ovary pressure/pain and I've got 20+ full sized follies in there.
2. Religious or moral objections. I didn't have any of these.
3. Self-doubt about bringing in the big guns when they're not necessary. I didn't give in to IVF until we'd done four medicated cycles, done IUI, went through all the testing and bw they could throw at us. By the time we decided on IVF it was pretty obvious that if we want a baby any time soon, IVF was the way to go. Do I think we could get PG naturally if we tried long enough? Maybe. But we want 3-5 kids and I'm hitting 30 next month. I'm not going to spend any more of my early adult years on TTC that isn't working. I can't deal with that kind of stress, and frankly, times a tickin'.
4. Money. This part was really hard. We sold our house and moved to another country to be able to afford IVF. DH works from home, so it has been possible, otherwise I don't know what we would have done. For those who are in a similar position, overseas IVF can be a great choice. WE're getting a fresh cycle of IVF with all meds, procedures, and tests included, plus vitrification freezing and 3 years of storage, all for under $6000 USD. Add in the plane tickets here and back, and it's still cheaper than a cycle in the US. Plus, frozen cycles are only $2000 and we are already here, so no extra plane costs. (IVF where we lived would have been $14,000 USD after the cost of meds, and I don't think that would have covered freezing & storage.
5. Romantic ideas about how babies being conceived. This was my hardest part. Once we decided on IVF< I still wasn't sure I could go through with it. I don't know why, but even after we sold the house, I still wasn't sure. We closed on the house, moved into a temporary space, and still, I just wasn't sure. About two weeks after closing, I got a natural cycle BFN and it was just too much. I cried out all the regret and pain and I finally just let go of it all. Then I was ready for IVF. I don't know what it's like for others, but for myself I really had to let go before I could move on. There was a picture in my head of how things should be and it wasn't how they were. I had to mourn.
6. IVF can, and often does, FAIL. This doesn't bother me much. At least if we try, try, try, try, try and fail, we know that we have to move on to adoption. Baby or not, at the end of IVF, at least there is some amount of closure. I'm sure if we got to that point, there would be lots of mourning again, but at least there would be an answer.