My Lo started on sma and tommee tippee bottles, suffered badly with colic and reflux, changed to aptamil and noticed huge difference but was still suffering slightly, when lo was finally diagnosed with reflux and put on infant gaviscon i changed to dr brown bottles and they were both the best changes I have ever made, I highly reccommend aptamil and I defo would never go back to tommee tippee bottles, yeah dr browns are more expensive but worth every penny, he was a changed baby overnight, but that said all babies are different. I just know until I changed bottles his colic was that bad he would spend hours and hours from 5pm screaming in pain, within days of changing he was in a routine and goes to bed at 7.30pm, he also wouldn't sleep in his Moses basket, just my bed and the same day I put him in his basket and that was it, I've never looked back, coincidence mayb but I dnt think so. Xx