It should be fine, but I have heard that for some babies that are colicy that the concentrate or ready to feed worked better for them than the powdered. when my lo was a newborn and having bad gas issues, I tried the concentrate version of the same formula and didn't see a difference though so went back to the cheaper powder. I'd say start with getting a small container of the powder and see how it goes, if the colic symptoms get worse, go back to the cartons for a little while until lo outgrown the colic.