ivf girls.... 10% fragmentation.. How bad is it?

[LadyLovenox]

Got my day 2 embryo report. Out of my ten embryos, 7 are at the 4-cell stage, which is apparently ideal. However they ALL have 10% fragmentation. My online research says everything from "anything under 20% is normal", to "Fragmented embryos rarely implant". I don't know what to believe or how to feel. Any success with 10% Fragmented embryos?

 

[LadyLovenox]

No one's had fragmentation but me?? (

 

[oneof14]

Hey Lady, I've never been given my fragmentation, just the number of cells or whether the embryo was at blast, etc. sorry I can't be more helpful.

 

[chimmi]

Hiya I had two day 3 embryos transferred with fragmentation they didn't say how fragmented they were but they said they were "average with fragmentation" I've read that fragmentation is normal and doesn't mean it won't work. It didn't work for us but didn't want to read and run. Try not to worry.

 

[3chords]

I never got a fragmentation report on day 2, but did on day 3 so I am not really sure what to tell you.

This time around we didn't care what the fragmentation was (within reason) because we did PGS and with PGS the morphology no longer means anything really.

 

[LadyLovenox]

Thank you all soo much for your responses!!! I got my update call today which said that two of them "cleaned up" the fragmentation, and the others are at 5-10% now... So much better (I hope!!) 5 of them have 8 cells, and the others have 5 or 6.

3chords....really interested to know... Were any of the Fragmented embryos "normal" in the pgs testing? I always wonder if the only ones that are "normal" are perfect 8 cell, 0% fragmentation, day 3 embies... Or if some of the 5-6 cells or ones with fragmentation are still actually "normal"....

 

[3chords]

3chords....really interested to know... Were any of the Fragmented embryos "normal" in the pgs testing? I always wonder if the only ones that are "normal" are perfect 8 cell, 0% fragmentation, day 3 embies... Or if some of the 5-6 cells or ones with fragmentation are still actually "normal"....

Really good question!

I honestly don't know if they were fragmented as I didn't ask (and I'm assuming fragmentation was ok since they froze them fine).

The best looking (and my only) 8-cell day 3 embryo was PGS abnormal (monosomy 2 I believe). The next best looking embryo was a 7-cell day 3 and that one was PGS normal. The next best after that was a 7-cell day 3 that looked really nice and this one was a complex abnormal. One of my 6-cell day 3s caught up and became an expanded blast on day 6 and was PGS normal.

 

[LadyLovenox]

Wow.... Its all so interesting!!! Thanks for sharing!! I can never believe how unpredictable this all is!! Who would think your 6 cell would be "better", chromosomally than your 8 cell!

 

[3chords]

Yeah, for sure, who knows how many transfers I'd have had before they got to the 6-cell one...

I forgot to say that all the ones that were 5-cells on day 3 were abnormal for me. Last time I had 2 5-cell day 3 embryos transferred and one stuck and I had a m/c so now I am thinking they were probably abnormal...