Soos
Mommy!
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i've seen couple of posts over here saying to drink tonic water against leg cramps. tonic water is potentially dangerous to drink during pregnancy and breastfeeding
Pregnancy
Quinine crosses the placenta; one study found the cord plasma concentration to be approximately one-third the concentration of quinine in maternal plasma. Studies in rabbits and guinea pigs have shown that quinine is teratogenic. However, no teratogenic effects were seen in mice, rats, dogs, or monkeys.
Quinine has been used to treat patients in the third trimester of pregnancy with P. falciparum malaria. However, the risk of quinine to the fetus must be balanced against the danger of P. falciparum malaria, which is potentially life-threatening, especially during pregnancy. Studies in humans have shown that quinine causes congenital malformations, especially when given in large doses (e.g. up to 30 grams for attempted abortion).
These malformations include deafness related to auditory nerve hypoplasia, limb anomalies, visceral defects, and visual changes. In addition, quinine may have an oxytoxic action on the uterus and has been shown to cause abortion when taken in toxic amounts. Stillbirths have also been reported in mothers taking quinine during pregnancy. Quinine should only be given to pregnant women where the benefit gained greatly outweighs the risk.
Breastfeeding
Quinine is excreted in breast milk in small amounts. One study suggests that a breastfed infant will receive approximately 1.5 - 3.0mg per day of quinine base from maternal therapy. Problems in humans have not been documented.
Pregnancy
Quinine crosses the placenta; one study found the cord plasma concentration to be approximately one-third the concentration of quinine in maternal plasma. Studies in rabbits and guinea pigs have shown that quinine is teratogenic. However, no teratogenic effects were seen in mice, rats, dogs, or monkeys.
Quinine has been used to treat patients in the third trimester of pregnancy with P. falciparum malaria. However, the risk of quinine to the fetus must be balanced against the danger of P. falciparum malaria, which is potentially life-threatening, especially during pregnancy. Studies in humans have shown that quinine causes congenital malformations, especially when given in large doses (e.g. up to 30 grams for attempted abortion).
These malformations include deafness related to auditory nerve hypoplasia, limb anomalies, visceral defects, and visual changes. In addition, quinine may have an oxytoxic action on the uterus and has been shown to cause abortion when taken in toxic amounts. Stillbirths have also been reported in mothers taking quinine during pregnancy. Quinine should only be given to pregnant women where the benefit gained greatly outweighs the risk.
Breastfeeding
Quinine is excreted in breast milk in small amounts. One study suggests that a breastfed infant will receive approximately 1.5 - 3.0mg per day of quinine base from maternal therapy. Problems in humans have not been documented.