hopestruck
Mommy to a Miracle
- Joined
- Nov 19, 2011
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Good morning ladies!
How is everyone doing? Annie? Jumik? Bex, are you hanging in there??![Heart <3 <3](/styles/default/xenforo/smilies/PurpleHeart.gif)
AFM, I did a bunch of research on antithrombin deficiency over the weekend. THere seems to be a mix of good and bad news. Here is what I found out:
- hereditary disorder, so if I have it, I probably got it from my mom or dad, which means my brother may also be affected
- because it's hereditary, there is a 50:50 chance of passing it on to my baby![Cry :cry: :cry:](/styles/default/xenforo/smilies/cry.gif)
- extremely rare...1 person in ever 2000-5000 has it
- the major risk factor for antithrombin deficiency is blood clots in the legs or lungs, or stroke, but other potential problems can be recurrent miscarriage (!)
- personal risk factor depends on a few things, but the best indicator is how many clots or strokes are in your personal or family history (THIS is good news, because NO ONE in my immediate family has had any clots or strokes?!?! Only exception was my grandpa who had a lung clot (pulmonary embolism while he was on his deathbed in the hospital this past summer. But that could have been totally unrelated)
- treatment is usually through an anticoagulant/blood thinner...
- during pregnancy you are predisposed to a higher risk of blood clots (as with everyone), but it is worse if you have the antithrombin deficiency. Blood thinners are usually given to protect both mother and baby
- there are a lot of unknowns about treatment. Heparin (lovenox) requires antithrombin receptors to work. So reduced antithrombin may mean that heparin is not very effective (since there's nothing for the heparin to bind to). Because it is such a rare issue, there is very little research and no clinical trials. In many cases heparin seems to work, and then you have to switch to an oral or IV blood thinner during birth and post-partum.
So.... WOW!
How is everyone doing? Annie? Jumik? Bex, are you hanging in there??
![Heart <3 <3](/styles/default/xenforo/smilies/PurpleHeart.gif)
AFM, I did a bunch of research on antithrombin deficiency over the weekend. THere seems to be a mix of good and bad news. Here is what I found out:
- hereditary disorder, so if I have it, I probably got it from my mom or dad, which means my brother may also be affected
- because it's hereditary, there is a 50:50 chance of passing it on to my baby
![Cry :cry: :cry:](/styles/default/xenforo/smilies/cry.gif)
- extremely rare...1 person in ever 2000-5000 has it
- the major risk factor for antithrombin deficiency is blood clots in the legs or lungs, or stroke, but other potential problems can be recurrent miscarriage (!)
- personal risk factor depends on a few things, but the best indicator is how many clots or strokes are in your personal or family history (THIS is good news, because NO ONE in my immediate family has had any clots or strokes?!?! Only exception was my grandpa who had a lung clot (pulmonary embolism while he was on his deathbed in the hospital this past summer. But that could have been totally unrelated)
- treatment is usually through an anticoagulant/blood thinner...
- during pregnancy you are predisposed to a higher risk of blood clots (as with everyone), but it is worse if you have the antithrombin deficiency. Blood thinners are usually given to protect both mother and baby
- there are a lot of unknowns about treatment. Heparin (lovenox) requires antithrombin receptors to work. So reduced antithrombin may mean that heparin is not very effective (since there's nothing for the heparin to bind to). Because it is such a rare issue, there is very little research and no clinical trials. In many cases heparin seems to work, and then you have to switch to an oral or IV blood thinner during birth and post-partum.
So.... WOW!