July testers - Over 35

[Macwooly]

Mon_n_john hope you get the answers you need and deserve

 

[Mon_n_john]

Wendy, I hope that AF comes on it's own. I will pray for you!

LL, glad you got the confirmation you needed. I would highly recommend the progesterone. Liek I said, I had 3 mcs before my last son and the only thing I did different with his pregnancy was prog. and a baby asprin a day. Who knows what worked but I know prog. can't hurt. I take mine from 7 DPO - 14 DPO unless I am pregnant and then I continue till 14 weeks.

As for me my blood test went fine, I was a big, brave girl lol. They took 3 vials so not so bad. They are testing for Antiphospholipid (APA), Embryotoxicity Factor, and Reproductive Immunophenotype. The tests should be back within 2 weeks which will be a nail biter! I am $766 poorer but hopeful this will lead to some answers. = )

I hope you get every answer you are looking for! Does your insurance not cover any investigation?

They do cover some stuff and I have fought for them to cover my chromosomal testing. Still can't believe they actually paid for that! But the immune testing? They'll never pay for it and the lab that does the tests doesn't even accept insurance since no insurance in the US covers it. Ugh! It's OK though, we've set money aside for this and I rather know for sure, you know?

 

[Mon_n_john]

By the way, I had the loveliest dream last night. I dreamt I took a HPT and 2 pink lines came up right away! I was soooo excited but I remember thinking, no way, I think I dipped the test too long. So I took another one out, repeated the test, and sure enough BFP! I've never had a dream about testing before, not ever. I hope it's a sign of good things to come!

 

[Wishing4abump]

Hi ladies!

Wendy - that sounds like an awful drug. I hope that your levels come down on their own and that you can then move on to your next cycle. It's been such a hard week for you. At least you have some answers now.

LLbean- I'm so sorry that you ended up with a chemical. You have such a pma though. Good luck for next month.

Afm af did not arrive yesterday as expected and no sign today as yet. but did test with frer this am (not fmu) and still getting a . Really unsure as to what's going on. It's unusual for me to late - I checked back and haven't been late in the last 12 months. no symptoms though but bbs so seem to be a little tender on top today. Surely a bfp would be showing up now at 1 day late?

 

[Desperado167]

Mon-n-John,wot are the two other blood tests for?I have been tested for the sticky blood but they won't test me for the immune system tests ,i have just had my tenth mc ,xxxxxx

 

[Mon_n_john]

Mon-n-John,wot are the two other blood tests for?I have been tested for the sticky blood but they won't test me for the immune system tests ,i have just had my tenth mc ,xxxxxx

Antiphospholipid (APA) - Antiphospholipid antibodies are proteins that circulate around in the bloodstream. These proteins bind to cell membranes, making them sticky. This prevents our blood from flowing properly, resulting in blood clots. These antibodies can endanger the health of both you or your baby. Treatment consists of low dose asprin (which I am on already) and/or heparin. So I guess this is the sticky blood test!

Embryotoxicity Factor - This test basically tests for things in your blood that may attack the developing embryo. It is said that 30-40% of women with several miscarriages show positive for this factor. It is usually treated with cortisone therapy.

Reproductive Immunophenotype - Identification of the type of relative concentrations of various white blood cell populations in blood is valuable in determining risk factors for pregnancy loss. The Reproductive immunophenotype has been shown to be useful in identifying individuals at risk for not implanting embryos and for loosing karyotypically normal pregnancies due to elevated circulating Natural Killer (CD56+) cells. The Activated Reproductive Immunophenotype measures not only the percentage of circulating lymphocytes as the Reproductive Immunophenotype does, but also activated NK and T cells. Women experiencing implantation failure after IVF/ET have significantly higher expression of NK cell activation marker of CD69+ and of T cell activation marker of HLA-DR. Treatment for women who have an elevation of NK cells consists of immunologlobulin G infusion (IVIg).

I know it's a heavy read but that should give you a rough idea lol. Some of this stuff is very interesting. Do you know how they test for the embryotoxicity factor? They take 20 blastocysts from 5 different mice and basically test to see if your blood stops the mice embryo from developing, eeek!

I had to pay out of pocket for the test but my RE recommended it and what she recommends, I do lol. I would get more testing Desperado!

 

[Jennjenn]

Mon - it is very interesting! I am totally amazed at what science can do. I had actually googled them when you posted earlier. Good luck I hope you get some answers...

 

[Desperado167]

Mon-n-jon I have asked for the tests and they said they don't do them in northern Ireland,I wud have to go to england but they have suggested treating me
With both heparin and cortisone injections if I get another bfp,I am 44 ,not too sure if I could see a fertility specialist at my age ,but I have an apt at my doc in four weeks and am gonna speak to her about getting referred and theses tests,thanks a lot for the info Hun,xxxxxxxxxxxxx

 

[dachsundmom]

Despie, does NHS have an upper age limit?

 

[Mon_n_john]

You are very welcome Despie. Here in the states I don't believe we have an age limit at the fertility specialist. You could always come here lol! But I do know it's very expensive.

I know you can have the tests sent out from your country to another country for testing so it is a possibility.

 

[Wendyk07]

Wendy - this is from wikipedia...it says waiting only 1 full cycle...I know doctors tend to be more conservative and that is probably why they gave you the 3 month waiting period. But holy f*** this drug also treats cancer!

Women must not take the drug during pregnancy, if there is a risk of becoming pregnant, or if they are breastfeeding. Men who are trying to get their partner pregnant must also not take the drug. To engage in any of these activities (after discontinuing the drug), women must wait until the end of a full ovulation cycle and men must wait three months

Thats exactly what i read. oh and the bit that says that you can bleed for 6 weeks.

 

[Mon_n_john]

Mon - it is very interesting! I am totally amazed at what science can do. I had actually googled them when you posted earlier. Good luck I hope you get some answers...

Thanks a bunch Jenn. I am such a science geek, I love this stuff!

 

[Wendyk07]

just got back from my doctor's office...chemical...my doctor was nice and she says if I want she can write me a prescription for progesterone but says that scientifically it has not been proven to make a difference...either way I got in with the fertility specialist for tomorrow at 1pm!

Finally someone listens to you re the progesterone. I hope this works for you hun and next cycle there is a sticky bean.

 

[Wendyk07]

Wendy this Methotrexate sounds full on lets hope you start naturally. Just been reading up on it

LL

I actually have been physically sick at the thought of this. My nerves are shattered.

 

[Wendyk07]

Wendy, I hope that AF comes on it's own. I will pray for you!

LL, glad you got the confirmation you needed. I would highly recommend the progesterone. Liek I said, I had 3 mcs before my last son and the only thing I did different with his pregnancy was prog. and a baby asprin a day. Who knows what worked but I know prog. can't hurt. I take mine from 7 DPO - 14 DPO unless I am pregnant and then I continue till 14 weeks.

As for me my blood test went fine, I was a big, brave girl lol. They took 3 vials so not so bad. They are testing for Antiphospholipid (APA), Embryotoxicity Factor, and Reproductive Immunophenotype. The tests should be back within 2 weeks which will be a nail biter! I am $766 poorer but hopeful this will lead to some answers. = )

OMG! two whole weeks.

I hope you get the answers that you are looking for.

 

[Jennjenn]

Wendy - this is from wikipedia...it says waiting only 1 full cycle...I know doctors tend to be more conservative and that is probably why they gave you the 3 month waiting period. But holy f*** this drug also treats cancer!

Women must not take the drug during pregnancy, if there is a risk of becoming pregnant, or if they are breastfeeding. Men who are trying to get their partner pregnant must also not take the drug. To engage in any of these activities (after discontinuing the drug), women must wait until the end of a full ovulation cycle and men must wait three months

Thats exactly what i read. oh and the bit that says that you can bleed for 6 weeks.

F***in A - I didn't see the part about 6 weeks bleeding - that's miserable. I guess that is why it is 3 month wait. Is there any reason why they aren't considering a D&C? It's what I had when I had my MC...

 

[Jennjenn]

Mon - it is very interesting! I am totally amazed at what science can do. I had actually googled them when you posted earlier. Good luck I hope you get some answers...

Thanks a bunch Jenn. I am such a science geek, I love this stuff!

Me, too! drives me crazy sometimes...

 

[Mon_n_john]

Wendy this Methotrexate sounds full on lets hope you start naturally. Just been reading up on it

LL

I actually have been physically sick at the thought of this. My nerves are shattered.

You poor baby, you have every right to be nervous. It sucks that you are going through this but we are all here for you honey.

 

[Wendyk07]

Hi ladies!

Wendy - that sounds like an awful drug. I hope that your levels come down on their own and that you can then move on to your next cycle. It's been such a hard week for you. At least you have some answers now.

LLbean- I'm so sorry that you ended up with a chemical. You have such a pma though. Good luck for next month.

Afm af did not arrive yesterday as expected and no sign today as yet. but did test with frer this am (not fmu) and still getting a . Really unsure as to what's going on. It's unusual for me to late - I checked back and haven't been late in the last 12 months. no symptoms though but bbs so seem to be a little tender on top today. Surely a bfp would be showing up now at 1 day late?

I just wish i had a diagnosis before i have to take this drug. They are clutching at straws.

Test again tomorrow hun. The frers i believe are 25miu so there just might not be enough HCG in your system yet. F'xd for you.

 

[dachsundmom]

for everyone!