We've been TTC#1 for almost 14 years. We have had BFP's (one ectopic July '08, three early miscarriages October '98, July '09, June '11, one chemical March '11, and one second trimester loss July '10)
I have PCOS, but am on metformin and as far as anyone can tell, ovulate regularly. DH has no problems. You name it, we've tried it, from natural suppliment (Soy, agnus castus, etc) right up to and including using up all our cycles of NHS funded IVF. There's no cause found for our losses either. We're apparently just "unlucky"