Hi ladies, I'm just dipping in here to highlight uterine natural killer cells...
A bit about myself ttc #1 for 5 years, I had an initial abyss of 9 months ttc and nothing happened...had a laparoscopy and started using opks...following month I fell pregnant, ended in miscarriage at 5 weeks .. Not sure how I managed to get pregnant, perhaps it was having the laparoscopy as one tube needed a bit of resistance to flush dye through or using opk.... Through the sticks I realised that I ovulate anywhere between cd14 to around 21!!
Since then I've had 5 early miscarriages and on ethical loss at 17 weeks(Down syndrome and extensive heart defect..)
Anyhow I'm here to bring to attention to uterine natural killer cells...
After 6 losses, 5 of which were naturally conceived... Had 2 lots of IUI and fell pregnant with my longest pregnancy( few weeks after starting medication for under active thyroid,specifically hashimotos an auto immune form of under active where body's immune system attacks the thyroid gland,incidentally it is one of the most common types.)
Had 2lots of ivf one of which no eggs were fertilized, however on first cycle I had 5 eggs fertilise and look like fantastic eggs,any one could have been transferred, however in view of the fact that I was 41 we paid extra to have the chromosomes checked and 2 of the 5 were chromosomally normal,both were transferred though none took, since this happened since July last year I have had one more miscarriage in August this year, it limped on to 7 weeks with assistance of steroids and progesterone pessaries...further than other 4 miscarriages..
I need more answers I already knew that the hashimotos could be a cause of early miscarriage, and was aware from extensive reading that abnormal uterine natural killer cells were also a cause of early miscarriage, both these conditions in as much as 50% of cases are linked....
So I had the uterine biopsy done recently and sure enough I now have a diagnosis of abnormal uterine natural killer cells.... So my treatment will continue to be steroids, with a few tweaks in medication...
I am well aware I may never fall pregnant again and forever live in hope...
The reason I am posting this on a lttc forum is that some of you may be thinking of going down the ivf route....and I suppose what I would like to get accross is that if you have an auto immune disease chances are it's highly likely you may have aggressive natural killer cells in your uterus also....
Many women who have never been pregnant go down the line of failed ivf attempts ( often at great monetary expense as well as emotional) and then look for other answers, often case is they can well find out through investigation that aggressive natural killer cells are to blame..
The biopsy cost me £360 only few places in England do this,I'm in Scotland and had to travel down...
I am sure lots of women already know about this, but I want to reach out and highlight my story and perhaps, alert someone to this possibility of why they may not be concieving...
A bit about myself ttc #1 for 5 years, I had an initial abyss of 9 months ttc and nothing happened...had a laparoscopy and started using opks...following month I fell pregnant, ended in miscarriage at 5 weeks .. Not sure how I managed to get pregnant, perhaps it was having the laparoscopy as one tube needed a bit of resistance to flush dye through or using opk.... Through the sticks I realised that I ovulate anywhere between cd14 to around 21!!
Since then I've had 5 early miscarriages and on ethical loss at 17 weeks(Down syndrome and extensive heart defect..)
Anyhow I'm here to bring to attention to uterine natural killer cells...
After 6 losses, 5 of which were naturally conceived... Had 2 lots of IUI and fell pregnant with my longest pregnancy( few weeks after starting medication for under active thyroid,specifically hashimotos an auto immune form of under active where body's immune system attacks the thyroid gland,incidentally it is one of the most common types.)
Had 2lots of ivf one of which no eggs were fertilized, however on first cycle I had 5 eggs fertilise and look like fantastic eggs,any one could have been transferred, however in view of the fact that I was 41 we paid extra to have the chromosomes checked and 2 of the 5 were chromosomally normal,both were transferred though none took, since this happened since July last year I have had one more miscarriage in August this year, it limped on to 7 weeks with assistance of steroids and progesterone pessaries...further than other 4 miscarriages..
I need more answers I already knew that the hashimotos could be a cause of early miscarriage, and was aware from extensive reading that abnormal uterine natural killer cells were also a cause of early miscarriage, both these conditions in as much as 50% of cases are linked....
So I had the uterine biopsy done recently and sure enough I now have a diagnosis of abnormal uterine natural killer cells.... So my treatment will continue to be steroids, with a few tweaks in medication...
I am well aware I may never fall pregnant again and forever live in hope...
The reason I am posting this on a lttc forum is that some of you may be thinking of going down the ivf route....and I suppose what I would like to get accross is that if you have an auto immune disease chances are it's highly likely you may have aggressive natural killer cells in your uterus also....
Many women who have never been pregnant go down the line of failed ivf attempts ( often at great monetary expense as well as emotional) and then look for other answers, often case is they can well find out through investigation that aggressive natural killer cells are to blame..
The biopsy cost me £360 only few places in England do this,I'm in Scotland and had to travel down...
I am sure lots of women already know about this, but I want to reach out and highlight my story and perhaps, alert someone to this possibility of why they may not be concieving...
Have you tried intralipid iv at all? THis is supposed to help too. At least you know what your problem is and can get pregnant. It's just terrible that you have struggled so much. Have you tried a naturopath in order to also see which foods make you have inflammatory response? I did a test with ~300 different foods and was really shocked at which ones my body puts up a defense to. Eggs, oats, wheat, and nightshade vegetables (cauliflower, broccoli etc). I've been eating badly this past week and have had wicked bad arthritis in my knees and have bloodshot eyes everyday. Bloodshot eyes is a classic sign of massive inflammation in your body. I'm mostly a meat and vegetable girl now which as helped me feel SO much better and lose a ton of weight. Inflammation is a killer too when it comes to ttc. I find a plan and more information always helps me feel more confident going into the next try. 
