Anybody just started Metformin? - Need Buddy

[hopeful64]

Hey Ladies! I have PCOS too and was just put on Actoplusmet 15/500mg, which is a combination of Actos and Metformin. I'm yet to see anyone else here on this combo drug.
My RE said he prefers this drug over metformin especially for those who are not overweight. And it is supposed to be better tolerated than plain metformin.

I started taking one tablet daily in the beginning of April and was supposed to go up to 2 tablets daily after one week, then I came down with a stomach virus and had to stop taking it for a week and half. I started taking it again last friday, so I will increase to 2 tabs a day tomorrow. Side effect has been pretty mild. I only have mild nausea every once in a while, never had diarrhea.

Last Af was February 23rd, I hope this med helps bring one soon.

Hi Hopeful!
I think there are lot of different forms of Metformin. Yours is probably just one of them. Your side effects however DO sound very mild! No diarrhea is amazing! I had bad diarrhoea for the first week and whenever I increased my dosage....but no more diarrhoea now.

Do you usually have regular AFs? Metformin is supposed to regulate your AFs....What's the dosage that your doc wants you to be on?

Wow@ diarrhea for one week! I guess I'm lucky. My RE recommended taking pepcid (an antacid) 30 mins before taking my med, as it is supposed to help lessen the stomach side effects.

Actoplusmet like I said earlier is a combination of 2 different meds used in diabetes pts. I'm on Actoplusmet 15mg/500mg, which is Actos 15mg combined with metformin 500mg. I started taking one tablet once a day and I'm going up to twice a day today. My RE wants me to take it for 3 months to sort out my hormones (hopefully), before he adds clomid to that. Hopefully I get a bfp before I get to go on clomid.

My Af is no way near regular. I can go up to 4 months without.

 

[miahleemom]

Hi all,
I just started taking met yesterday. My dr gave me 1000 mg 2x a day. I feel horrible, when will the side effects start to go away? Is there a remedy for the nausea and diarhea that won't effect ttc? The fatigue is also driving me crazy!!!

Hey! I think 2000mg to start is REALLY high! Didn't your doc advise you to take it incrementally??!?? I'm supposed to go up to 2,000mg too, but I started at 500mg first..... Most women would advise you to start at a lower dosage....But then again, if your side effects go away after 1 week, you would have the entire side effects all at one go and no more incremental side effects...... Still, if your side effects are too bad, I'd suggest calling your doc to ask if you can reduce your dosage to start....

I did 500mg for 1 week, followed by 500mg x 2 for another 5 days and tried to increase to 500mg x 3 for 5 days - but it didn't work, cos I developed migraines. So I decreased it to 500mg x 2 for 3 weeks again before increasing to 500mg x 3 again over the past week and I've had no additional side effects. Praise God!!!!

I think you'd need to listen to your body and see how well it takes Metformin.

I am going to stick with what the doctor has said about the 2000mg a day and I have also heard of the amazing success stories with the dosage that high. It's bearable so I guess I will manage. Just haven't left the house in a few days. How long have you been taking it for?

 

[cheerios]

Hi all,
I just started taking met yesterday. My dr gave me 1000 mg 2x a day. I feel horrible, when will the side effects start to go away? Is there a remedy for the nausea and diarhea that won't effect ttc? The fatigue is also driving me crazy!!!

Hey! I think 2000mg to start is REALLY high! Didn't your doc advise you to take it incrementally??!?? I'm supposed to go up to 2,000mg too, but I started at 500mg first..... Most women would advise you to start at a lower dosage....But then again, if your side effects go away after 1 week, you would have the entire side effects all at one go and no more incremental side effects...... Still, if your side effects are too bad, I'd suggest calling your doc to ask if you can reduce your dosage to start....

I did 500mg for 1 week, followed by 500mg x 2 for another 5 days and tried to increase to 500mg x 3 for 5 days - but it didn't work, cos I developed migraines. So I decreased it to 500mg x 2 for 3 weeks again before increasing to 500mg x 3 again over the past week and I've had no additional side effects. Praise God!!!!

I think you'd need to listen to your body and see how well it takes Metformin.

I am going to stick with what the doctor has said about the 2000mg a day and I have also heard of the amazing success stories with the dosage that high. It's bearable so I guess I will manage. Just haven't left the house in a few days. How long have you been taking it for?

Hi! I have been taking it for about 2 months now. Got my AF after one month so I'm waiting for my next AF to come!

 

[KnitWit]

Hello ladies,

Ive been away from the forum for a bit, after I was diagnosed with PCOS I needed some time to get my mojo back. I too have just started taking Metformin (day 5 today!). Im taking 500mg a day at the moment but have been advised to gradually increase that to 2000mg a day. Had my HSG this week too which was awful but I had a sweet nurse who held my hand through the painful parts. And I came out with the good news that my tubes are clear

Just wondering, how soon did you ladies start to see the effects? Did you have to wait till you were on the full dosage before your periods settled down? Mine can be anywhere from 32 - 65 days long. Crossing my fingers that I have a nice normal cycle this month but don't want to get my hopes up

 

[cheerios]

Hey Knitwit!
We're in the same boat. I'm currently on 2,000mg (1,000mg x 2 daily). I also started on 500mg and gradually increased it to 2,000mg. The side effects were not pleasant to say the least, but now its not too bad. I got AF after 1 month of taking 1,000mg Metformin. But so far, my next AF hasn't come yet. I really still hope that it will come by the end of May!

Congrats that you got clear tubes though! That's something to rejoice about!