Want2bMum - you should read a bit more on the clomid.....
It wont make you O earlier than normal when taking it earlier.
As far as I know if you take is day 3-7 you'll have more eggs released and higher chances of multiples. if you take it from day 5-9 it will give a more mature egg.....something like that.
what i understand of clomid is that it is a synthetic estrogen which binds to estrogen receptors, they need to be fully occupied for your pituitary gland to start secreting fsh which in turn switches on secretion of lh triggering maturation of follicles and release of an egg...
by day 5 of your cycle you should have already started production of estrogens so clomid is a further help, this is what it was designed for and marketed for.
Doctors have noticed through blood tests and ultrasounds that for many women with very delayed ovulation and absent ovulation, their body doesn't start this mechanism or it starts it too late. It is as if your body is at rest or has a very low production activity, therefore giving clomid before day 5 starts up this chain mechanism.
It usually takes the body from 5 to 10-12 days to respond to this high and synthetic occupation of receptors, therefore the sooner you start the sooner you you respond and ovulate.
For what i know, there isn't any research looking at follicle production in different days of intake of clomid, my guess is that if some specialist says this, they may be speaking out of experience rather than scientific research, which is acceptable anyway, i am not saying it is not.
Last cycle i took it day 5-9 and it took me 11 days to respond, i will probably have the same reaction time any day i take it, as far as it is the same dose, so instead of ovulating on day 20 i'll maybe ovulate on day17...
As or multiples, the only study conducted is the one reported in the leaflet and of course scientists couldn't take into consideration familiarity first of all because for monozygous twins the mechanism is unknown and also because many times people do not know...
overall, chances of multiple pregnancy is increased by 10%...
Going by this, i am keen on taking it day3-7 but of course i still have some doubts... in the end of the day it was marketed for day5-9 and my specialist seems to think that's the best way of taking it...