Inconceivable and beyond :-)

[2have4kids]

Hi Mrs G, I'm having very few pregnancy symptoms other than chronic hunger pangs due to the hormones. My next scan is Friday and then the Nauchal Translucency scan March 27th.
How was everyone's weekend? The weather is cold & windy just miserable here right now. Just makes me want to hibernate.

 

[Mrs G]

2have, I'm the same, very little to report. Really hot at night and occasional v slight nausea but that's all. I've got a scan next thurs and midwife next Tuesday. Just ticking off the days!
Xx

 

[crystal443]

Can't wait to hear about your next scan 2have!!

It's warm here, evenings are cool and days are warm

 

[Pussycat1]

Ladies good luck with the forthcoming appointments!
Coolstar, how did your appointment go?
I've had a reply from the dr at Reprofit which basically said there's no reason they can pinpoint and possibly just bad luck but our frosties are top quality so he's sure I'll get pregnant with them. The only change he suggested was to change from prednisone 5mg to medrol (Metypred) 8mg. I've emailed back with a big list of questions so hopefully his reply will clarify things for me a bit. Not sure what the difference between the two steroids is, 2have any ideas?
X

 

[2have4kids]

Ladies good luck with the forthcoming appointments!
Coolstar, how did your appointment go?
I've had a reply from the dr at Reprofit which basically said there's no reason they can pinpoint and possibly just bad luck but our frosties are top quality so he's sure I'll get pregnant with them. The only change he suggested was to change from prednisone 5mg to medrol (Metypred) 8mg. I've emailed back with a big list of questions so hopefully his reply will clarify things for me a bit. Not sure what the difference between the two steroids is, 2have any ideas?
X

I think Crystal would probably be better to answer this but it looks like another form of prednisone to me. Still a very very low dose for someone with NKC's, I'm on 20 mg prednisone for inflammation, I don't even have NKC's. My diet helps with inflammation and the D & B vits that I take have studies showing they take down inflammation too. Crystal I believe was on 25mg and on an anti-inflammatory no sugar/salt diet too. When I looked up Metypred, it has reactions with estrogens, it "weaken(s) the immunosuppressive action methylprednisolone" when you're on estrogens - just good to be aware of that if you do use the prescription/dosing from Reprofit.
- https://www.leki-informacje.pl/jamnik/img/galeriaplikow/3/metypred_spc.html

I think a prednisone prescription from your immunologist would be much more effective (and you might get an appropriate dose) than your fs. fs is going to give you the minimums to keep your worries satisfied while protecting his own behind. He makes babies, he's not worried about immunology, nor are they specialists in that area. Reprofit did this with me too, put me on the minimums. My immunologist finally pulled out the big guns once I had my diagnosis

Are you able to get IVIg in your area too? I really hope an FET works, hopefully there aren't many more costs other than immune treatments with your next round.

 

[Pussycat1]

2have, I don't have an immunologist nor can I afford one. I can't get a prescription for IVIG as I don't have a private dr in the UK (only NHS and they won't prescribe) , and I doubt I can afford that even if I could get it . The UK system is very different and insurance rarely covers fertility, and definitely not when your 44. I'm close to admitting defeat I have neither the time money or energy for this anymore. AF arrived today so I'm feeling particularly crap. x

 

[2have4kids]

PC, I'm sorry you're feeling crap and have little support. I've got some really wide eyed star gazed looks from my doctors in Canada but thankfully I could probably ask for whatever dose I want and they'd set me up. I'm sorry you're hitting road blocks with yours.
Hey you Brits did just pass a bill that allows for 3 way fertilization using mitochondria or some sort of RNA something missing from the egg. That's a step in the right direction and ahead of any other country. Even if you did have the dosh for all that stuff (IVIG/humira etc), when I did it, it STILL didn't work. Just hang onto your frosties and see what happens. We all have f&tx for you!

 

[Mrs G]

Pussycat, massive hugs. It's complete shit hun and I'm so sorry you're having to go through this. I don't know anything about nkc I'm afraid, but like 2have I'm on 25 prednisone
and have never had any testing. The system in this country is so unfair and so sporadic. I can understand the feeling of having had enough. I used to wonder if I could fight it anymore. You are strong hun and we are all here for you.

Coolstar, how are you?

Hi to everyone.
Xxx

 

[2have4kids]

Last Friday I asked my doc about chromosomal testing and she shrugged saying that if the nauchal translucency scan comes back in high ratio of having Down's Syndrome or 3 other similar defects we'd talk about it after May when I return from my vacation so I did a little digging and there's a Pegasus study being done in my city. So they accepted me as a candidate today, will administer the test at exactly 10 weeks (a vial of blood) and know if my baby has anything wrong one week later. Normally women pay $900 here for this test. The usuall process is to find a place that will send bloodwork to the USA when the nauchal translucency scan comes back with high chances of Down's Syndrome. The blood test avoids an invasive amniocentesis or chorionic villus sampling. Both pose risks to fetus.
I feel so relieved, just to not have that stress of more $$ for more tests. We were going to have the results from the nauchal test right before we leave with a potential of stress over unclear results (imagine 1 in 10 for Down's Syndrome possibility??) hanging over our heads.

When things are crappy, they really are terrible and when things work out, sometimes ithe ouch just keeps going

 

[Coolstar]

2have, I am keeping my fingers Xed for you.
PC, just hang in there girl. You are very strong and you really inspire me. Even I was on 10 prednisone. I hope your next FET cycle works. When are you planning to go for your next FET ?
MrsG, Fxed for your scan. You were on prednisone after ET ?
About me, my doc doesn't want me to go for FET with our frozen embryos. Instead she wants us to use frozen donor egg.My AF has started today and she wants me to start BCP, have AF and then do a FET around mid April. We have decided to go ahead , for me I don't care much who's egg is it if I get a BFP with my DH's sperm. Ladies, do keep me in your prayers, I think my next FET would be our last try.

 

[dmama]

2have, I am keeping my fingers Xed for you.
PC, just hang in there girl. You are very strong and you really inspire me. Even I was on 10 prednisone. I hope your next FET cycle works. When are you planning to go for your next FET ?
MrsG, Fxed for your scan. You were on prednisone after ET ?
About me, my doc doesn't want me to go for FET with our frozen embryos. Instead she wants us to use frozen donor egg.My AF has started today and she wants me to start BCP, have AF and then do a FET around mid April. We have decided to go ahead , for me I don't care much who's egg is it if I get a BFP with my DH's sperm. Ladies, do keep me in your prayers, I think my next FET would be our last try.

Coolstar - so great to hear you have a plan! I used frozen eggs and had success the first time. It is a good plan if your RE herself doesn't think that the embryos you have are viable. Hope this helps!

 

[dmama]

2have, I don't have an immunologist nor can I afford one. I can't get a prescription for IVIG as I don't have a private dr in the UK (only NHS and they won't prescribe) , and I doubt I can afford that even if I could get it . The UK system is very different and insurance rarely covers fertility, and definitely not when your 44. I'm close to admitting defeat I have neither the time money or energy for this anymore. AF arrived today so I'm feeling particularly crap. x

Pussycat - Hugs to you. Hope that a doc can help you get on top of the immune stuff if that is what might be interfering with implantation.

 

[2have4kids]

Coolstar hoping a change of plan works!

 

[Mrs G]

Hi everyone.
Coolstar, strange they froze your embies bit now won't use them. Do glad you have a plan tho. I've been on predisolone since ec so 5 days before ET and will be on it in reducing doses til 10 weeks.
Pussycat hope you've had an ok day hun.
Xxx

 

[2have4kids]

Those of you on Prednisone, do you find that it makes you feel winded? I do cardio everyday and find that I'm sweating profusely and can't seem to catch my breath now, it's annoying. I'm on it till 25 weeks out. Can't wait to get off the stuff. I was taking 2 in the morning and 2 in late afternoon(20mg) but the doctor said it's got a long half life and I can take all 4 in the morning and then it'll be less likely to affect my sleep. It's working thankfully.

PC & coolstar how are you doing?
How about everyone else?

 

[Mrs G]

2have, I'm on 25mg once a day and have been having night sweats. Not noticed breathlessness but feel really hot and dehydrated. Being on so many drugs it's hard to pin down what is down to which one!!
X

 

[sienna]

2 have getting the tests for free is good, fingers crossed your tests come back ok
Coolstar I’m glad to hear you have a plan, has your doc said why they don’t want you to use your frozen embryos

how's everyone else doing?

 

[Coolstar]

Sienna, my doc said that since out of the 10 eggs fertilised 5 did not survive and the quality of the 5 that survived is ok but not that good so she does not want to go ahead with that set of embryo's.
PC, how are you ?
My AF has started and it's back with vengeance . It's cramping and very heavy .

 

[LLbean]

Last Friday I asked my doc about chromosomal testing and she shrugged saying that if the nauchal translucency scan comes back in high ratio of having Down's Syndrome or 3 other similar defects we'd talk about it after May when I return from my vacation so I did a little digging and there's a Pegasus study being done in my city. So they accepted me as a candidate today, will administer the test at exactly 10 weeks (a vial of blood) and know if my baby has anything wrong one week later. Normally women pay $900 here for this test. The usuall process is to find a place that will send bloodwork to the USA when the nauchal translucency scan comes back with high chances of Down's Syndrome. The blood test avoids an invasive amniocentesis or chorionic villus sampling. Both pose risks to fetus.
I feel so relieved, just to not have that stress of more $$ for more tests. We were going to have the results from the nauchal test right before we leave with a potential of stress over unclear results (imagine 1 in 10 for Down's Syndrome possibility??) hanging over our heads.

When things are crappy, they really are terrible and when things work out, sometimes ithe ouch just keeps going

May I jump in on this thread? I'm very curious on this test 2have! I'm keeping my best thoughts for you! Please let me know!

Hugs to you and all, hope to join and be bump buddies soon ;-)

 

[crystal443]

2have that is great news about the testing �� will be keeping fingers crossed for you as always. As for the sweats and heart racing... Yep I always get that on steroids and get winded quicker. Just take things a bit easy if your getting side effects

Pussycat, immune treatment is very expensive ��

Liz, hi lovely lady ��

Hi everyone