Waiting to start IVF in January anyone else?

[Libby4snoopy]

Hi Ladies. Can I join here. Myself (35yrs) and my DH (33yrs) have a 3yr old daughter conceived without any issues. However we have been trying to conceive a sibling for 2yrs now without any success. All my tests have come back normal , DH SA has showed low morphology. We have been advised ICSI and so I have begun injections 3 days ago on the 29th Dec(CD21. Im excited but also scared of being disappointed and would welcome any support or advise you could offer. ALso has anyone experienced any side effects from the injections?

 

[HisSweetheart]

Hello,

Me too joining this group.. I had my 1st IVF, ER in Dec'14, but ET was not done due to thing endometrium lining. So awaiting natural FET this month or next month depending on the lining. As on y'day it was CD11 6.4mm triple lining. Have 2 day3 Grade B 8-celled embies in the freezer. Hoping for the best!...

 

[HisSweetheart]

@MoBaby and @nimbec - with these AMH values, did ur RE mention something on PCOS? bcoz one of the other person who posted here mentioned that she had PCOS so she also had a high AMH... is that always true??

@star25 - woohoo.. thats a gr8 number... 22 eggs, 20 fertilized !!...

If any of you who've got ur ER report, can u tell me what was mentioned against the "Egg/Oocyte Quality" field? I know, the report format may vary across different clinics, but just curious to know.

 

[nimbec]

Star25 yay for a transfer buddy hopefully the time will fly by! Is the round very different? As obviously no EC but do you follow the same protocol?

Welcome hissweetheart fx you lining is super and you can get those enmbies on board!

I do have pcos well appear to have as my blood work and appearance of ovaries say I have but I'm a light pcoser as I am not overweight at all so they treat a little different apparently - I take Metformin too. Will be interesting to see how many eggs I get fx they do t under stim me it's one of my concerns!

Welcome libby4snoopy sorry I can't offer advice as not started injections yet - interested to hear everyone's answers!

 

[HisSweetheart]

Nimbec, when are you starting the injs? Are you on the antagonist protocol or the agonist?.. I guess with the mild pcos, u wont be under stimmed, infact you could respond well.

I do not have pcos, and so was put on the antagonist protocol... my RE is a really patient and understanding person, but I suppose she got too greedy to extract more mature eggs and me stimmed for 12 days. Luckily for her, she got 8, all mature, mission accomplished. DH's SA came back fine, everything looked so rosy, she insisted on standard IVF rather than ICSI. Alas!.. only 3 fertilized and 2 made it to day3 with grade-B. At this point she became conservative and hesitated to let them progress upto 5th day, so froze the remaining 2 on day3. So much for "lateral impression" of my eggs and DH's sperm!...

Then I had a detailed discussion with RE and she told that, my eggs had some amount of SER (some morphological anomaly, which may or maynot affect implantation and pregnancy.. let me not go into tmi, as its already a long post..), due to which the eggs could not fertilized normally through IVF (so ICSI cud hav been done!.. but late realization..). She told that many donor eggs also have it, but REs dont take it so seriously, bcoz SER eggs do produce healthy babies.
Apparently, its the healthy eggs that may progress to have SER before ER, if ur stimulation is longer, and increases 3 times with a short protocol / antagonist protocol. So usually only long protocols are suggested for patients with pcos or those who had an instance of SER in previous ER.

This was a lot of blah blah... My case was a late realization, but I hope this info is of some use to people with PCOS or SER+ cycles, and I hope RE's know well, and suggest appropriate protocols on a case-to-case basis.

Libby, as far as my experience goes, I didnt have any negative side effects other than having really heavy feeling bbs and sore nips. And I guess I put on a pound or 2 extra, but cant be so sure to attribute the weight gain to the stims...

 

[star25]

Hi Libby and welcome, hope all goes well, I'm the same, so excited but so scared of getting a bfn
The main side effects I had was ovary pains and tiredness, though I did overstimulate so the ovary pains were bound to happen!
I'm not sure of my amh but they said I had busy ovaries so does was probably too high

Hissweet, hopefully we can have transfers around the same time, I cant wait, I'm doing fet due to overstimulation
As weve been lttc for years and had a good number of eggs they wanted to do standard ivf on half and icsi on the other half to see if it was a case of eggs and sperm not meeting/bonding together
Out of it 9 fertilised with icsi and 11 standard ivf
Just want to get started now after having to wait for transfer

 

[FirstTry]

Welcome, Libby and Sweet! :wave:

I'm on day 8 of stims and the main side effects I'm having are bloating and fatigue.

Today, I have 18 measurable follies! I think this is pretty good, right?

5@13mm
2@12mm
6@11mm
3@10mm
2@9mm

My translocation means that 2/3 of my eggs are chromosomally abnormal, so I kind of need 3x the eggs.

 

[MoBaby]

First that is great!!! Fx you get plenty of normals

His: I do not have pcos. My AMH is borderline high right now but not pcos level. I ovulate normally and never overstim.

 

[beneathmywing]

Welcome, Libby and Sweet! :wave:

I'm on day 8 of stims and the main side effects I'm having are bloating and fatigue.

Today, I have 18 measurable follies! I think this is pretty good, right?

5@13mm
2@12mm
6@11mm
3@10mm
2@9mm

My translocation means that 2/3 of my eggs are chromosomally abnormal, so I kind of need 3x the eggs.

Great numbers!

 

[AngienDaniel]

Micro-IVF cycle is pretty short and sweet. I have 100mg Clomid for 5 days, 1Bravelle injection for 2 days, then I guess a trigger shot and egg retrieval/transfer. I am very glad that I am able to do a micro cycle. You women that do a full IVF cycle are amazing to me. I am scared to death of messing up the two little shots I have to take. I can't imagine all the shots in a full cycle.

What does having PCOS have to do with over-stimulating? I have a high AMH --4.3 last time I was told.. Ha Ha! I thought that number was good! I have not been told I have PCOS though. Is it a given if you have a high AMH? I have never had a cyst though, at least for sure not in the last three years. What does it have to do with over stimulation? What can you do to prevent it? What effect does fertility meds have on a 'thin' PCOS'er compared to a 'not thin' PCOS'er?
Trying to get info from women who have been there and not have to find out I am dying by reading Dr. Google.

 

[Libby4snoopy]

Thanks for the kind welcomes ladies. The last 2 days of injections have been followed by fatigue and bad lower back pain for me-similar to the kind I experienced when pregnant before. Have noticed nothing in my bbs yet! I don't really no anything about AMH levels so sorry I cant really be of any help to anyone around this.

 

[star25]

Nimbec my protocol is

CD1 - baseline scan then start estradiol 4 tablets a day

CD11-13 - follicle tracking scan to make sure not going to ovulate or have already ovulated ( withnmy track record and long cycles no chance!)

Then probably another scan to make sure lining is thick enough etc then transfer, day of transfer have injecton of buserelin and carry on with estradiol tablets amd progesterone pessaries then hopefully a bfp!

 

[nimbec]

First try they look great fx you get lots of normal ones - when is collection booked for?

Angien high AMH does not necessarily mean pcos - an ultrasound would show pcos and also blood tests. AMH is just an indication of how many eggs are available. Ladies with pcos 'can' have more readily available.
Studies have found that 30% of slim women with PCOS have insulin resistance, however it affects as many as 75% of those who are overweight. I'm not sure that the meds are different based on weight - more on whether you have the insulin resistance or not. Hopefully this has helped - I maybe wrong but this is what I have understood lol!

They often recommend the mini ivf protocol when women have high AMH and I was offered this but then they changed their mind as my eggs tend to get stuck at a certain size so I may need more to make them grow to full size!

I have a question ladies - I know we are not allowd sex before cd21 when I start northisterone but can we do it whilst I'm on northisterone? Just wondering I'm guessing when I'm injecting I won't feel like it ... Hope you don't mind me asking!

 

[1stbaby4me]

Hi ladies, I had my initial ultrasound with my new clinic today, cd3. My RE is still on vacay so a different doctor performed my ultrasound. I have cycts on both ovaries and a little bit of fluid in my left tube. I'm supposed to have cd21 med start date but I'm not sure now. I have to meet with billing on jan 13 then I get my schedule from the nurse. I'm hoping the cycts will disappear during suppression and the fluid will clear up once af is gone. Im excited and scared to start this roller coaster ride for thr 3rd and possibly last time.

 

[lizzie78]

Nimbec we were allowed all the way through down regging and stims last time right up until transfer and then nothing until I got my bfn. Have to say though I didn't really feel very up for it!!

 

[FirstTry]

Nimbec: they told us not to have unprotected sex at all once the cycle starts. Maybe they're afraid of competition My egg retrieval is expected around Jan 8-10, I think.

Good luck, 1stBaby! I hope this is your lucky cycle!

 

[FirstTry]

Micro-IVF cycle is pretty short and sweet. I have 100mg Clomid for 5 days, 1Bravelle injection for 2 days, then I guess a trigger shot and egg retrieval/transfer. I am very glad that I am able to do a micro cycle. You women that do a full IVF cycle are amazing to me. I am scared to death of messing up the two little shots I have to take. I can't imagine all the shots in a full cycle.

So, my DS was actually the result of a medicated IUI where I over-responded and produced 9 eggs. So, we converted to IVF at the last minute. The key for me was shots of Gonal-F on days 5 and 7, along withChlomid. So, I can see how your mini-cycle could work well. Fingers crossed!

 

[nimbec]

Thanks ladies I'm sure I won't feel like it either but it's nice to know. I'm pretty sure I can't currently as I'm not at cd 21 yet for northersterone so there in theory is a chance I could get pg- yeah right!! That's a joke isn't it lol!!!

Star that sounds great not too many nasty drugs enough but not too many! Fx for that bfp!

Firstbabyforme fx all still goes to plan! If it helps I have a long standing cyst 3.5cm that I have had over a year & they are happy to proceed with it.

 

[star25]

Nimbec, I'm not sure on the sex q but so glad you asked as I had completey forgotten your meant to have unprotected sex until day of scratch!

1st, I hope it works out and you can still start the medication for your cycle

First, you have a good amount of follicles there will you have another scan before egg collection?

Afm, phoned nirse yesterday as dont want to have scratch then mot get af for another month so she said 5 days after the scratch start to take the provera, I normally get af 10 days after starting provera so that would make it 3rd Feb to start meds and hopefully transfer middle of Feb, so relieved they said I can do this and wont have any hold ups!

 

[FirstTry]

Nimbec, I'm not sure on the sex q but so glad you asked as I had completey forgotten your meant to have unprotected sex until day of scratch!

1st, I hope it works out and you can still start the medication for your cycle

First, you have a good amount of follicles there will you have another scan before egg collection?

Afm, phoned nirse yesterday as dont want to have scratch then mot get af for another month so she said 5 days after the scratch start to take the provera, I normally get af 10 days after starting provera so that would make it 3rd Feb to start meds and hopefully transfer middle of Feb, so relieved they said I can do this and wont have any hold ups!

I'll have scans everyday now.

I've never had the scratch, but I'm a believer in it. It seems to help with implantation.