I had/have hyperemesis and I started feeling a bit better around 14 weeks. I was able to start weaning off the meds at about 16 1/2 weeks. I was taking 3/day, now I strive for 1. It ebbs and flows - some days I am so hungry and 1 is great. Other days I could care less about eating, have more aversions/nothing sounds good feelings, and need two pills. I am not constantly nauseous, so that is the most welcome change of them all. I more feel like there is a rock in my stomach...lol, but I'll take that over constant, crushing nausea any day. I feel VERY lucky and I hope my luck continues.