7th Natural cycle IVF(w/o meds) and finally BFP!

[Electricat]

Briss, could you please explain to me how that "trigger shot"? works?

You take the block medicine for the last days to have every follicle grow as much as possible - then you trigger? Is the trigger LH? If so, why is that given? Isn't there a danger of the LH popping the follicles and they miss the eggs?
I didn't quite get what she told me on the consultation - something about 36 hours before you get the ER-appointment? I would be scared of my follicles popping ahead of time!

I guess what I'm trying to ask is why do you need the LH when they're gonna stick a needle in the follicles anyway?

 

[Briss]

they need trigger so they could time EC perfectly. timing is everything it has to be just right not too early so the egg is mature and not too late not to miss the egg. eggs grow inside follicles but as far as I know they properly mature after LH surge and are ready to be released 36-48 hours after the LH surge. they do not want to wait for your natural LH surge cos it can start at any hour randomly and they wont be able to time EC that's why they suppress your natural LH and instead trigger with artificial LH at a certain hour (once they are happy with the follicles size) and do EC exactly 36 hours later. there is always a risk that your natural LH surge will override suppression. it happened to me last IVF so they put me on some other medication to preserve the follicle between the surge and EC. when you go for EC you are never 100% sure you have not ovulated yet, there is always a small risk.

 

[Electricat]

they need trigger so they could time EC perfectly. timing is everything it has to be just right not too early so the egg is mature and not too late not to miss the egg. eggs grow inside follicles but as far as I know they properly mature after LH surge and are ready to be released 36-48 hours after the LH surge. they do not want to wait for your natural LH surge cos it can start at any hour randomly and they wont be able to time EC that's why they suppress your natural LH and instead trigger with artificial LH at a certain hour (once they are happy with the follicles size) and do EC exactly 36 hours later. there is always a risk that your natural LH surge will override suppression. it happened to me last IVF so they put me on some other medication to preserve the follicle between the surge and EC. when you go for EC you are never 100% sure you have not ovulated yet, there is always a small risk.

Ah ok, thank you.
So there is an element of uncertainty about the surge, cuz I was thinking what if my body is more "sensitive" to LH surge and I pop all my egg baskets after 24 hours you know?
I've just seen on my OPKs that they go from very faint to a dark line quickly and often I have temp rise very shortly after, sometimes the same day as pos OPK. So it made me think my bubbles burst easily within surge - if I make any sense. Maybe if I tell them my suspicion they have some backup plan. Or if I'm completely off my rocker, they can tell me so and I'll be fine. I guess they've done this before - hehe

Tnx for explanation

 

[Briss]

my temp went up on the morning of EC and I had all the usual symptoms confirming that i ovulated. I was so sure I ovulated but they did a scan before EC and my follicle was still there

 

[Electricat]

Maybe stay off the temping? Just not to freak out? Did you do OPKs?

 

[Briss]

my LH went up despite taking the meds so they asked me to do OPK. it was negative but then about 3-4 before I was supposed to do the trigger it turned positive. i called the clinic but they said it was OK but I need some additional meds. I asked the doc at EC about temping and she said they do not rely on temp but they do trust OPK

 

[Briss]

not great news from today's scan, two left follicles have grown nicely at 19/20 mm but the third one at 16 mm has grown on the right side right above my cyst and they said the cyst is not a simple one cos it has blood inside so they wont be trying to collect that egg because the risk of puncturing the cyst and infection is just too great. So if we are lucky we will get two eggs. My lining is all ready at 13.3 mm. I triggered tonight and EC is scheduled for Tuesday. fingers crossed!!

I asked again about such poor response to meds but it seems like everyone has a different opinion. today's doc said we should try (hopefully we wont have to though) to start with the large dose from CD2 and will possibly get much better result. seems like some think we should stick to natural while others believe more stims are needed. how confusing, seems like there is no simple answer.

finaly got my notes from our previous IVF and apparently our 2 day embryo was graded 4cl/1f, seems ok but i do not really like "f", do not know what it means but it cant be good.

 

[bettybee1]

Hmmmm how long you been stimming for ??? And what dose ?

I would suggest if this doesn't work which am hoping it does that you go somewhere else that will stimulate you properly and accordling too get A good amount off eggs hunnie especially with your right been out off bounds ?

Or even get your cyst aspirated. ? X

 

[Electricat]

You can do it, Briss - I'm cheering for you!!
I have no knowledge of this stuff, so I don't understand why they can't just suck the cyst out at EC.
It's what they do with the normal follicles anyway. But I guess there is a good reason...like that it would act like a water balloon with a needle and not like a plastic bag with water in it.
Your lining is perfect though, so very good chance of implantation

Good luck.

 

[Briss]

Thanks ladies, unfortunately that's not a type of cyst that can be aspirated. it can be removed during a lap surgery but most likely with part of the ovary which is a no for me cos at the moment at least the ovary is ovulating on its own (although not much use of that with low sperm count). I had 9 days of stims: 5 days on 125 Gonal F and 4 days on 250. We could try a different clinic or a different protocol but with high FSH the odds are really against us. hoping and praying…

 

[bettybee1]

Urghh 9 days on that low dose is not long at all Hun

Really you should off be started on 300mlu and then adjusted accordling xxx

 

[Briss]

EC was, to put it mildly, disappointing. Only one mature egg. I had a temp rise this morning and suspected I ovulated and turned out I was right. one of the two follicles on the left disappeared. Somehow, the doc managed to get one more egg from my right ovary without touching the cyst so we had 2 eggs collected but the lab just confirmed that only one egg was mature for ICSI. anxiously waiting for the news on fertilisations tomorrow.

had a bit of a breakdown when we got home, all the stims etc and the result is no better than we would have got from a completely natural cycle. I will spare you what my DH had to say on the matter but he is very upset. Mainly with the clinic for making me go through the stims and for missing the egg. The doc said there was no way to prevent early ovulation.

I feel quite sick and distressed. trying to calm down

 

[bettybee1]

am sorry hun glad you have one tho

wasnt you on cetrodie ?/?// :000000

really think if this cycle doesnt work which i hope it does that you need too find a better clinc there crap !!!1

who starts a lady off on 125mlu of bloody gonal-f which isnt as good as menpour especailly in high fsh ladies i feel angry for you


you should off started off on at least 300-350mlu off menpour then when follicles get to 10mm your given cetriode it stops ovulation from occuring then on your tracking scan if things are growing too fast they knock your dose down lower if things are okay they keep you the same and stim you normally for at least 12 days xxx

 

[Electricat]

Ah crap, Briss
Did you get any BD in? Maybe you caught the eggie on your own?
In any case - you only need one, right?

Crossing my fingers for you!

bettybee1 - I'm on 125 of Gonal f and my FSH has been 19. My Dr. (and later my nurse) didn't even flinch. I brought it up and they both just went, "meh, you had 11 follicles, you've been pregnant before - this is a go".
I'm worried they're just taking my money and not really giving me good advice.

Again, Briss - good luck, I'm cheering for you

 

[bettybee1]

obvouisly what i say about it is just what i ahve heard from docters etc and other people

but my docter started me on 225 menpour i have pco and only 20 at the time my fch is 4-5 my amh 24 !!


its okay to start on a low dose aslong as if you aint responding they up it

but i think menour is the better one as it has LH in aswell and helps the follice mature aswell xxx

 

[Briss]

Thank you ladies. I was on cetrotide for the last 4 days of stims and stopped before trigger. but my LH was rising even while on cetrotide but I did OPK at 6 pm on the night of trigger and it was negative. looks like I ovulated the next day after trigger. so much for 36 hours...

They wanted 3 days of abstinence for DH so we did not BD since saturday

my clinic does not seem to use menopur for stim cycles only in modified natural. I was on 150 last cycle for 5 days from CD 6 and had 2 follicles.

 

[bettybee1]

defo if it doesnt work get to a new clinc none of this "'modified"" mild its just a money making game

 

[Briss]

bettybee, clinics do not accept ladies with FSH above 15 for IVF. I talked to a few top IVF clinics in London and that's what they said. i guess they do not want to ruin their stats. it's very depressing. I really hope this cycle works for us. I am exhausted tbh. I have booked a visit to Lister in January, it's a private clinic that works with high FSH ladies so maybe they will suggest something else.

 

[Briss]

my only egg did not fertilise. they told me it was not good quality. I was very suspicious when they did not give me meds for the entire 2 weeks just for a few days. I guess they already knew that the chances of fertilisation were slim but did not tell me. strange after all this talk on how great my blood flow was and that I am to expect good quality eggs. The embryologist mentioned that the meds might have affected egg quality because my egg was of good quality on the previous natural cycle. maybe the one they missed was the only good one this cycle. My husband blames the clinic, 6K down the drain + me having to go through the stims and the result is worse than in a natural cycle. It's the end of the road for this cycle. this is going to be the hardest TWW ever with no hope whatsoever. I am in pieces and cant even think clearly where we go from here. totally devastating...

after 2 failed cycles, DH does not want any more IVF until next summer. he said it's his turn to take the drags (he struggled to see me going through stims) so finally agreed to see a urologist. I just cannot stop crying

 

[bettybee1]

Am so sorry Hun as I had 2 failed cycles diff circumstances I can Relate it's depression and a horrid feeling ,

I think nhs hosptials take high fsh ladies ? You self fund through them everything is cheaper ? Maybe try that ?

Also waiting till next summer is going too add an extra year too your eggs?

What's your amh ? X