Hey, Mommylov, you mentioned you had a low progesterone issue along with w/a MTHR gene mutation. I assume for that, you were taking Folgard (or whatever it's called!). Now, I don't know if you've done this already, but I too had progesterone issues, and I was put on 50 mg of Clomid (although I WAS ovulating, just not strongly enough...), and that can significantly boost progesterone, and help you produce a BETTER QUALITY egg. Once pregnancy is confirmed, or 3 dpo, you can begin doing the progesterone supplements, either vaginally or orally, to help support the higher level that the Clomid produced. For me, that was the ticket. Just something to bring up and ask your RE about!