Hollyoaks will kill off five main characters in next week's dramatic episodes, while the new Hollyoaks Later series will feature two other deaths, Digital Spy can confirm.
Show bosses have lined up some of the biggest storylines in Hollyoaks history to help celebrate the programme's 18th birthday in style.
The explosion erupts through the Kane's home.
As previously reported, a huge explosion will rock the village's council flats next week after Sinead O'Connor accidentally brings a bomb into Ste Hay and Doug Carter's leaving party.
Sinead thinks that she has stolen a bag full of cash from local bad boy Trevor Royle, but in reality it contains a ticking timebomb which will cause devastation in the village.
The explosive device is in the bag as superbitch Clare Devine has escaped from prison and is plotting to blow up The Loft while Mercedes McQueen celebrates her 30th birthday inside.
As the situation comes to a head, ruthless Clare wrestles over the detonator with Trevor, who tries his best to calm her down and warns that people will die if she presses it.
The main characters in danger will include Mercedes, Carmel, John Paul, Theresa, Clare, Trevor, Ste, Doug, Sinead, Leanne, Dennis and Darren.
Ash, Dodger and killer Will are also in trouble as the blast impacts on the nearby Kane family home.
With five characters set to lose their lives next week, some will die in the council flat stunt, while others are expected to meet tragic fates in other circumstances.
Meanwhile, the new series of Hollyoaks Later will also include some shocking twists.
Digital Spy can reveal that there will be two deaths in the after-dark series, bringing the total number of casualties this fortnight to seven.
Show chiefs have also launched an official Hollyoaks Tumblr page https://hollyoaksofficial.tumblr.com/ which will provide exclusive gossip on the possible victims of the Blast storyline as the story unfolds.