March LuckyCharms 59 Tester's 15 BFP'S
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Dannixo
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Hi Danni,
Please take off my bfp I mc this one aswell
Im sorry to hear ab and confuzion its not a pleasant thing to go through.
Confuzion I am having recurrent mc aswell and have had all the tests done. It's not due to my endometriosis or my pcos as I can get pregnant I just can't seem to carry them past 5-6 weeks. I am having a second opinion by the best gyno and fertility doc in our city so lets hope he can find a reason. I have a 5 year old who was a twin which I mc early and have had a mc in 2010 and two mc this year one in Jan and this one. I will let you know if he comes up with something knew. Best of luck for next time
Congrats to the other ladies for getting their BFP I hope you each have a H&H 9 months
I'm sorry dear. My thoughts and prayers are with you.
Dannixo
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I'm sorry dear. Look forward to seeing you in Aprils thread.
twinkie2
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Hall Family-I am so sorry to hear this, especially that you've had to endure this several times. Thinking of you, again so very sorry for your loss.
Congrats jessmke! H&H 9 months to you!!
Danni-I'm cheering on your right ovary for this cycle. Let's go righty!! You suck lefty
Congrats jessmke! H&H 9 months to you!!
Danni-I'm cheering on your right ovary for this cycle. Let's go righty!! You suck lefty
jen_niferRose
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sorry to those who have MC.. 
I was obsessing over the weekend about how FF changed my O date - But I really think its because of how on CD23 I got out of bed, went to the bathroom, then lied back down and took it.. So I tested my theory and after I took it normally today, I got up, went to the bathroom, lied back down and took it again - it was .20 colder than the first temp! which I believe is what happened on CD23. I took that temp and bumped it up and it changed my O date back to CD21.. Anyway gotta love obsessing about this stuff! lol
I will just have to wait and see what happens..
I was obsessing over the weekend about how FF changed my O date - But I really think its because of how on CD23 I got out of bed, went to the bathroom, then lied back down and took it.. So I tested my theory and after I took it normally today, I got up, went to the bathroom, lied back down and took it again - it was .20 colder than the first temp! which I believe is what happened on CD23. I took that temp and bumped it up and it changed my O date back to CD21.. Anyway gotta love obsessing about this stuff! lol
I will just have to wait and see what happens..
Navygrrl
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*Great big hugs to all those who have MC* I hope you all get your rainbow babies soon.
I seem to o'ing later than normal this cycle. I wonder if changing diet and exercise can affect that. Then again, my normal o date years ago was cd19, so who knows.
I seem to o'ing later than normal this cycle. I wonder if changing diet and exercise can affect that. Then again, my normal o date years ago was cd19, so who knows.
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Hello and I am sorry about your loss! I am on my 9th cycle since my loss this Summer. The baby was due March 13th and I am hoping that because I ovulated that day that I see a bfp and have another rainbow. GL to you!
NewMrsJones
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I'm out AF arrived today 3 days early so it's on to April for me.
Good luck to those still waiting.
Good luck to those still waiting.
Jaysbaby25
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I am so sorry to the ladies that mc this month! baby dust and good luck sent your way for next month!! 
baby dust and good luck sent your way for next month!! 
Lenka78
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Me too, I am so sorry for the ladies that had a mc. 
I would like to share an article with you, who knows, it maybe a help to you.
There is such thing as a MTHFR deficiency, which is related to recurrent pregnancy loss.
Link: https://www.stephenwellsmd.com/mthfr.htm
MTHFR (5,10-methylenetetrahydrofolate reductase what a mouthful ) is a specific gene found on a specific chromosome within every cell in every person The MTHFR gene produces an enzyme responsible for a multi-step process that converts the amino acid homocysteine to another amino acid, methionine. The body uses methionine to make proteins and other important compounds.
What is a MTHFR Mutation?
An abnormal change in gene structure, called a mutation, of the MTHFR gene can cause a disruption of the MTHFR enzymes normal function of breaking down homocysteine.
The two common MTHFR gene mutations occur at specific locations called positions along the gene. The one we generally test for is located at position 677. At this location, one amino acid base pair is different, in that Cytosine is replaced by Thymine. This mutation is thus called C677T. Another mutation we test for occurs at position 1298. At this location, Adenine is replaced by Cytosine and is therefore called A1298C.
MTHFR mutations are common. The mutations can be heterozygous meaning they occur only on one strand or allele of the chromosome, or they can be homozygous, occurring on both alleles. The frequency of a heterozygous C677T mutation is common, occurring in about 35% of the population. The homozygous C677T mutation is about 5-10% of the population. A mutation in A1298T is more common but is generally less problematic. The homozygous variety of A1298T occurs in 9% of the population. Another mutation involves both the C677T and the A1298T alleles. This is a compound heterozygous condition that occurs in approximately 17% of the population.
Okay, enough of MTHFR Science 101
How Does MTHFR affect Pregnancy?
If the MTHFR gene is malfunctioning, homocysteine can build up and cause problems, both in the cardiovascular system, but also with pregnancy. At this time, well confine this discussion to the impact on pregnancy.
Some MTHFR mutations are more serious than others as far as their ability to cause problems during pregnancy. Specifically, women who have multiple pregnancy losses are more likely to have a MTHFR gene mutation.
The association of MTHFR and recurrent pregnancy loss is under great debate. Some clinicians and researchers feel that the mutations can cause blood clots between the developing placenta and uterine wall, thus preventing transport of vital nutrition to the developing fetus. This usually occurs early in pregnancy when the embryo or fetus is most vulnerable.
It is unlikely that the exact mechanism of how MTHFR affects pregnancy loss will be worked out in the near future. As a result, women and clinicians need to understand that there is no set standard of care protocol for dealing with recurrent miscarriage in the presence of a MTHFR mutation.
What Therapy is available for women with MTHFR Mutations?
Two scenarios that I feel benefit from therapy include the homozygous C677T mutation, and what is termed compound heterozygote mutation: heterozygous for both C677T and A1298T.
In these situations I feel administering daily injections of anti-clotting medicines Heparin or Lovenox give the best hope for women with a history recurrent pregnancy loss. The desired effect is to prevent clot formation between the developing placenta and uterine wall. Since the condition seems to affect pregnancies early, it makes sense to begin treatment early and continue well past the first trimester. Less clear is how long to continue treatment.
Additional treatments are daily administration of aspirin in low doses (St. Josephs chewable 81mg aspirin or generic). It is also of likely benefit to treat a woman with this condition with extra folic acid during the earliest part of her pregnancy, since the MTHFR condition tends to interfere with folate production. Folate is important in reducing Homocysteine levels, which protects against clot formation. This benefit, however, has been less well studied. Nevertheless Folgard 2.2 by prescription in addition to a prescription strength prenatal vitamin is also recommended.
Again, there is no evidence based standard to guide us. I will typically be more conservative and treat with Lovenox for longer in a womans first successfully treated pregnancy, and then may discontinue the treatment somewhat earlier in subsequent pregnancies. Again, this tends to be a first to early second trimester phenomenon.
I would like to share an article with you, who knows, it maybe a help to you.
There is such thing as a MTHFR deficiency, which is related to recurrent pregnancy loss.
Link: https://www.stephenwellsmd.com/mthfr.htm
MTHFR (5,10-methylenetetrahydrofolate reductase what a mouthful ) is a specific gene found on a specific chromosome within every cell in every person The MTHFR gene produces an enzyme responsible for a multi-step process that converts the amino acid homocysteine to another amino acid, methionine. The body uses methionine to make proteins and other important compounds.
What is a MTHFR Mutation?
An abnormal change in gene structure, called a mutation, of the MTHFR gene can cause a disruption of the MTHFR enzymes normal function of breaking down homocysteine.
The two common MTHFR gene mutations occur at specific locations called positions along the gene. The one we generally test for is located at position 677. At this location, one amino acid base pair is different, in that Cytosine is replaced by Thymine. This mutation is thus called C677T. Another mutation we test for occurs at position 1298. At this location, Adenine is replaced by Cytosine and is therefore called A1298C.
MTHFR mutations are common. The mutations can be heterozygous meaning they occur only on one strand or allele of the chromosome, or they can be homozygous, occurring on both alleles. The frequency of a heterozygous C677T mutation is common, occurring in about 35% of the population. The homozygous C677T mutation is about 5-10% of the population. A mutation in A1298T is more common but is generally less problematic. The homozygous variety of A1298T occurs in 9% of the population. Another mutation involves both the C677T and the A1298T alleles. This is a compound heterozygous condition that occurs in approximately 17% of the population.
Okay, enough of MTHFR Science 101
How Does MTHFR affect Pregnancy?
If the MTHFR gene is malfunctioning, homocysteine can build up and cause problems, both in the cardiovascular system, but also with pregnancy. At this time, well confine this discussion to the impact on pregnancy.
Some MTHFR mutations are more serious than others as far as their ability to cause problems during pregnancy. Specifically, women who have multiple pregnancy losses are more likely to have a MTHFR gene mutation.
The association of MTHFR and recurrent pregnancy loss is under great debate. Some clinicians and researchers feel that the mutations can cause blood clots between the developing placenta and uterine wall, thus preventing transport of vital nutrition to the developing fetus. This usually occurs early in pregnancy when the embryo or fetus is most vulnerable.
It is unlikely that the exact mechanism of how MTHFR affects pregnancy loss will be worked out in the near future. As a result, women and clinicians need to understand that there is no set standard of care protocol for dealing with recurrent miscarriage in the presence of a MTHFR mutation.
What Therapy is available for women with MTHFR Mutations?
Two scenarios that I feel benefit from therapy include the homozygous C677T mutation, and what is termed compound heterozygote mutation: heterozygous for both C677T and A1298T.
In these situations I feel administering daily injections of anti-clotting medicines Heparin or Lovenox give the best hope for women with a history recurrent pregnancy loss. The desired effect is to prevent clot formation between the developing placenta and uterine wall. Since the condition seems to affect pregnancies early, it makes sense to begin treatment early and continue well past the first trimester. Less clear is how long to continue treatment.
Additional treatments are daily administration of aspirin in low doses (St. Josephs chewable 81mg aspirin or generic). It is also of likely benefit to treat a woman with this condition with extra folic acid during the earliest part of her pregnancy, since the MTHFR condition tends to interfere with folate production. Folate is important in reducing Homocysteine levels, which protects against clot formation. This benefit, however, has been less well studied. Nevertheless Folgard 2.2 by prescription in addition to a prescription strength prenatal vitamin is also recommended.
Again, there is no evidence based standard to guide us. I will typically be more conservative and treat with Lovenox for longer in a womans first successfully treated pregnancy, and then may discontinue the treatment somewhat earlier in subsequent pregnancies. Again, this tends to be a first to early second trimester phenomenon.
Green Glitter
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So sorry for your losses Confuzion, AB, and Hall. (Hugs) With my last pregnancy it took me 3 MCs before I finally got one that took. 
I hope you all get your sticky beans soon!
I hope you all get your sticky beans soon!
Dannixo
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Hi ladies. Had my cd 3 ultrasound today and of course bad news again... I just can't get a break... I have 2 massive cysts the size of a baseball on my left ovary so we have another cancelled cycle and have to sit this month out. Good luck to everyone else!
