I don't know, 3C. I think they suggested CVS or amnio because there's a 4% chance of mosaicism (i.e., the cells they tested were normal, but the other cells were not). I'm going to follow up with my RE to get clarification.
But I agree that it would make more sense to do less testing rather than more.
I was told that the odds of mosaicism are more like 2% if you do a 5-day embryo biopsy with 3+ cells biopsied. Plus I always think, well the vast majority of Trisomy embryos would have miscarried anyway so the odds of one which has stuck around and was PGS normal are probably considerably better than 98%. I don't think I'm willing to do CVS or amnio until I've exhausted all other means. So if something funny pops up in the nuchal translucency test and the accompanying blood tests then I'd first do the Harmony test before moving on to more invasive tests.
Yeah, that makes sense. Maybe it's because we were not only testing for aneuploidy (wrong number of chromosomes), but also for UPD (two chromosomes from the same parent and zero from the other). UPD is a possible result of my translocation, and I don't think it causes miscarriage.
ILT: does an SCH make a cvs or amnio more risky? Btw, I've been bleeding on and off for 3 weeks now.