I am a nurse, and I will be the first to admit, that once you are in a specialized field of healthcare, you look at a patient and assume that because of their symptoms, they will get better with the plan of care that everyone else with those symptoms have benefited from!!! This is not the case....each patient should be looked at individually and the care plan should be indicated that way....So far this cycle I have taken vitex, B complex (with extra B 12) and now that I have ovulated, progesterone cream. The only difference I can tell so far is that I am having hot flashes and my breasts hurt already- which normally doesnt happen till my full bleed starts.....we will see if my spotting starts or not, which, in the past would be in about 5 days.